奥卡西平
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| 臨床資料 | |
|---|---|
| 读音 | /ɒks.kɑːrˈbæz.ɪˌpiːn/ |
| 商品名 | Trileptal, Oxtellar XR, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a601245 |
| 核准狀況 | |
| 懷孕分級 |
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| 给药途径 | 口服给药 |
| ATC碼 | |
| 法律規範狀態 | |
| 法律規範 |
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| 藥物動力學數據 | |
| 生物利用度 | >95% |
| 药物代谢 | Liver (cytosolic enzymes and glucuronic acid) |
| 生物半衰期 | 1–5 hours (healthy adults) |
| 排泄途徑 | Kidney (<1%)[1] |
| 识别信息 | |
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| CAS号 | 28721-07-5  |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.044.702 |
| 化学信息 | |
| 化学式 | C15H12N2O2 |
| 摩尔质量 | 252.27 g·mol−1 |
| 3D模型（JSmol） | |
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奥卡西平（英語：Oxcarbazepine，商品名：Trileptal等）是一种含氮有机化合物，分子式C15H12N2O2，可作为抗癫痫药物[1]，在体内的活性代謝產物为利卡西平[4]。
参考文献
[编辑]- ^ 1.0 1.1 1.2 Trileptal- oxcarbazepine tablet, film coated Trileptal- oxcarbazepine suspension. DailyMed. [9 November 2020].
- ^ List of nationally authorised medicinal products : Active substance: oxcarbazepine : Procedure no.: PSUSA/00002235/202108 (PDF). Ema.europa.eu. [5 June 2022].
- ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 31 March 2023 (4 April 2023) [16 August 2023]. （原始内容存档于3 August 2023） （巴西葡萄牙语）.
- ^ Oxcarbazepine Monograph for Professionals. Drugs.com. American Society of Health-System Pharmacists. [13 April 2019].
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