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上皮细胞黏附分子

此條目可参照英語維基百科相應條目来扩充。 (2024年2月1日)若您熟悉来源语言和主题,请协助参考外语维基百科扩充条目。请勿直接提交机械翻译,也不要翻译不可靠、低品质内容。依版权协议,译文需在编辑摘要注明来源,或于讨论页顶部标记((Translated page))标签。
EPCAM
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名EPCAM;, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, epithelial cell adhesion molecule, BerEp4, MOC-31, Ber-Ep4
外部IDOMIM185535 MGI106653 HomoloGene:1764 GeneCardsEPCAM
相關疾病
congenital diarrhea 5 with tufting enteropathy[1]
基因位置(人类
2號染色體
染色体2號染色體[2]
2號染色體
EPCAM的基因位置
EPCAM的基因位置
基因座2p21起始47,345,158 bp[2]
终止47,387,601 bp[2]
RNA表达模式
查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_002354

NM_008532

蛋白序列

NP_002345

NP_032558

基因位置​(UCSC)Chr 2: 47.35 – 47.39 MbChr 17: 87.94 – 87.96 Mb
PubMed​查找[4][5]
維基數據
檢視/編輯人類檢視/編輯小鼠

上皮细胞黏附分子(英語:Epithelial cell adhesion molecule,缩写EpCAM,也称为CD326,cluster of differentiation 326,分化簇326)是一种细胞表面跨膜醣蛋白,由人类2号染色体上的基因 EPCAM 编码,属于非钙依赖类细胞黏附分子,是上皮细胞的主要标志物[6]

参考文献

  1. ^ 與EPCAM相關的疾病;在維基數據上查看/編輯參考. 
  2. ^ 2.0 2.1 2.2 GRCh38: Ensembl release 89: ENSG00000119888 - Ensembl, May 2017
  3. ^ 3.0 3.1 3.2 GRCm38: Ensembl release 89: ENSMUSG00000045394 - Ensembl, May 2017
  4. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  6. ^ Litvinov SV, Velders MP, Bakker HA, Fleuren GJ, Warnaar SO. Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. The Journal of Cell Biology. April 1994, 125 (2): 437–46. PMC 2120036可免费查阅. PMID 8163559. doi:10.1083/jcb.125.2.437. 

外部链接

上皮细胞黏附分子引用了美国国家医学图书馆提供的資料,这些資料属于公共领域


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上皮细胞黏附分子
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