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KLF家族

Kruppel样转录因子家族(英语:Krüppel-like family of transcription factors,简称KLF家族)是一个锌指转录因子家族,其锌指结构为属C2H2型,与SP1英语Sp1 transcription factor样转录因子家族共同组成更大的Sp/KLF家族[1]

人类基因组中的KLF家族成员有[2]

KLF1、KLF2、KLF3、KLF4、KLF5、KLF6、KLF7、KLF8、KLF9、KLF10、KLF11、KLF12、KLF13、KLF14、KLF15、KLF16、KLF17

参考文献

  1. ^ Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, et al. A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. The Biochemical Journal. April 2011, 435 (2): 529–37. PMC 3130109可免费查阅. PMID 21171965. doi:10.1042/BJ20100773. 
  2. ^ McConnell BB, Yang VW. Mammalian Krüppel-like factors in health and diseases. Physiological Reviews. October 2010, 90 (4): 1337–81. PMC 2975554可免费查阅. PMID 20959618. doi:10.1152/physrev.00058.2009. 

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KLF家族
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