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野尻霉素

野尻霉素
IUPAC名
(3R,4S,5R,6R)-6-(Hydroxymethyl)-2,3,4,5-piperidinetetrol
识别
CAS号 15218-38-9
PubChem 65242
ChemSpider 21864922
SMILES
 
  • C([C@@H]1[C@H]([C@@H]([C@H](C(N1)O)O)O)O)O
ChEBI 28945
KEGG C06763
性质
化学式 C6H13NO5
摩尔质量 179.17 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

野尻霉素(英语:Nojirimycin)是一些链霉菌产生的5-氨基-5-脱氧-D-葡萄糖,为一种抗生素。形成吡喃环后,和葡萄吡喃糖相似,可以作为肠α-葡糖苷酶、胰α-淀粉酶,以及N-糖链加工中的α葡糖苷酶等的抑制剂。[1]

参考文献

  1. ^ Inouye, S.; Tsuruoka, T.; Ito, T.; Niida, T. Structure and synthesis of nojirimycin. Tetrahedron. 1968, 24 (5): 2125–44. PMID 5636917. doi:10.1016/0040-4020(68)88115-3. 
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野尻霉素
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