血绿素
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血绿素 （Chlorocruorin）是一种存在于多种环节动物（特别是多个多毛纲物种，例如龙介虫科）血液的血浆里的带氧蛋白[1][2][3]，负责为身体组织携带氧气。这种血绿素与氧气结合的亲和力较大多数的血红蛋白为低，但与一氧化碳结合的亲和力，是人血内的血红素的570倍[4]。
血绿素是一种（双色）化合物，其颜色随含氧量而变：脱氧时呈绿色，但带氧时呈红色；在浓度低的溶液呈绿色、浓度高时变浅红色[5][6][7]。
血绿素是一个巨大分子，但不存在于红血球内，而是自由地在血浆内漂浮[8][9]。其结构跟无脊椎动物血红蛋白非常相像；而无脊椎动物血红蛋白的结构又跟肌红蛋白（myoglobin）只有几个subunits的差异。它本身由多组16-17kDa的类肌红蛋白单元排列，形成一个有超过一百个单元的巨型复杂构造，蛋白间有互连，总重量超过3600kDa。The only significant difference between chlorocruorin and erythrocruorin is that chlorocruorin carries an abnormal heme group structure[8]。
参考文献
- ^ H. Munro Fox. The Blood Circulation of Animals Possessing Chlorocruorin. Proceedings of the Royal Society B. 1933-04-01, 112 (779): 479–495. JSTOR 81599. doi:10.1098/rspb.1938.0042.
- ^ R. F. Ewer, H. Munro Fox. On the Function of Chlorocruorin. Proceedings of the Royal Society B. 1940-08-09, 129 (855): 137–153. JSTOR 82389. doi:10.1098/rspb.1940.0033.
- ^ D.W. Ewer. The blood systems of Sabella and Spirographis. Quarterly Journal of Microscopical Science. 1941, 82 (s2): 587–619 [2010-05-01]. （原始内容存档于2008-10-06）.
- ^ Cowles, David. Serpula vermicularis Linnaeus, 1767. Invertebrates of the Salish Sea. Rosario Beach Marine Laboratory at Walla Walla University. 2006 [2011-10-31]. （原始内容存档于2011-10-02）.
- ^ H. Munro Fox. Chlorocruorin: A Pigment Allied to Haemoglobin. Proceedings of the Royal Society B. 1926-02-01, 99 (696): 199–220. JSTOR 81088. doi:10.1098/rspb.1926.0008.
- ^ H. Munro Fox. The Oxygen Affinity of Chlorocruorin. Proceedings of the Royal Society B. 1 September 1932, 111 (772): 356–363. JSTOR 81716. doi:10.1098/rspb.1932.0060.
- ^ H. Munro Fox. On Chlorocruorin and Haemoglobin. Proceedings of the Royal Society B. 19 October 1949, 136 (884): 378–388. JSTOR 82565. doi:10.1098/rspb.1949.0031.
- ^ 8.0 8.1 Pallavicini A, Negrisolo E, Barbato R; et al. The primary structure of globin and linker chains from the chlorocruorin of the polychaete Sabella spallanzanii. J. Biol. Chem. July 2001, 276 (28): 26384–90 [2016-03-17]. PMID 11294828. doi:10.1074/jbc.M006939200. （原始内容存档于2020-05-28）.
- ^ Lamy JN, Green BN, Toulmond A, Wall JS, Weber RE, Vinogradov SN. Giant Hexagonal Bilayer Hemoglobins. Chem Rev. 1996-12-19, 96 (8): 3113–3124. PMID 11848854. doi:10.1021/cr9600058 （英语）.
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