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莫拉司亭

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莫拉司亭
临床资料
AHFS/Drugs.com国际药品名称
ATC码
识别信息
ChemSpider
UNII

莫拉司亭(molgramostim),是一种重组粒细胞-巨噬细胞集落刺激因子,作免疫兴奋药英语immunostimulator之用[1][2],亦常与白细胞介素-2 、13-顺式维A酸等合用于治疗神经母细胞瘤高风险儿童患者[3]。莫拉司亭在临床上有较好的疗效,但不能排除其可能为肿瘤的生长因子,特别是由骨髓细胞产生的肿瘤,如急性髓细胞性白血病及慢性髓细胞性白血病等[4]

参考资料

  1. ^ Quittet P, Ceballos P, Lopez E, et al. Low doses of GM-CSF (molgramostim) and G-CSF (filgrastim) after cyclophosphamide (4 g/m2) enhance the peripheral blood progenitor cell harvest: results of two randomized studies including 120 patients. Bone Marrow Transplant. 2006, 38 (4): 275–84 [2019-09-26]. PMC 2100150可免费查阅. PMID 16883311. doi:10.1038/sj.bmt.1705441. (原始内容存档于2020-12-04). 
  2. ^ Orozco H, Arch J, Medina-Franco H, et al. Molgramostim (GM-CSF) associated with antibiotic treatment in nontraumatic abdominal sepsis: a randomized, double-blind, placebo-controlled clinical trial. Archives of Surgery. 2006, 141 (2): 150–3; discussion 154. PMID 16490891. doi:10.1001/archsurg.141.2.150. 
  3. ^ 医疗快讯:美国FDA批准抗肿瘤药Dinutuximab上市.中国执业药师.2015年.第6期:P24
  4. ^ 顾宏琼.治疗放化疗所致白细胞减少症的药物研究进展.中国药业.2010年.第13期:P87-88
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莫拉司亭
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