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脂肪栓塞综合征

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脂肪栓塞综合征(fat embolism syndrome)是指脂肪进入血液形成脂肪栓塞后表现的症状[1],通常在一天内开始[1],可能包括点状皮疹、意识水平下降和呼吸急促[1]。其他症状可能包括发烧和尿量减少[2]。死亡风险约为10%[2]

脂肪栓塞最常见的原因是股骨骨盆等骨骼骨折[3][1]。其他潜在原因包括胰腺炎整形外科手术骨髓移植抽脂[3][2]。该综合征底层的机制与广泛分布的炎症有关[3]。该综合征是基于症状来诊断的[2]

治疗主要是支持性护理[4],可能涉及氧疗静脉输液白蛋白和机械通气[2]。虽然骨折后血液中通常也会出现少量脂肪[3],但脂肪栓塞综合征其实很少见[4]

参考资料

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  1. ^ 1.0 1.1 1.2 1.3 Akhtar, S. Fat embolism.. Anesthesiology Clinics. September 2009, 27 (3): 533–50, table of contents. PMID 19825491. doi:10.1016/j.anclin.2009.07.018. 
  2. ^ 2.0 2.1 2.2 2.3 2.4 Laurence, Knott. Fat embolism syndrome. patient.info. 19 February 2014 [14 March 2018]. (原始内容存档于2017-12-01). 
  3. ^ 3.0 3.1 3.2 3.3 Adeyinka, A; Pierre, L. Fat Embolism. StatPearls. 2020. PMID 29763060. 
  4. ^ 4.0 4.1 Fukumoto, LE; Fukumoto, KD. Fat Embolism Syndrome.. The Nursing Clinics of North America. September 2018, 53 (3): 335–347. PMID 30100000. doi:10.1016/j.cnur.2018.04.003. 

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脂肪栓塞综合征
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