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白三烯C4合酶

白三烯C4合酶
已知的结构
PDB直系同源搜索: PDBe RCSB
识别号
别名LTC4S;, entrez:4056, Leukotriene C4 synthase
外部IDOMIM246530 MGI107498 HomoloGene:7406 GeneCardsLTC4S
基因位置(人类
5号染色体
染色体5号染色体[1]
5号染色体
白三烯C4合酶的基因位置
白三烯C4合酶的基因位置
基因座5q35.3起始179,793,980 bp[1]
终止179,796,647 bp[1]
直系同源
物种人类小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_145867
​NM_000897

NM_008521
​NM_001313968

蛋白序列

NP_665874

NP_001300897
​NP_032547

基因位置​(UCSC)Chr 5: 179.79 – 179.8 MbChr 11: 50.13 – 50.13 Mb
PubMed​查找[3][4]
维基数据
查看/编辑人类查看/编辑小鼠

白三烯C4合酶(英语:Leukotriene C4 synthase)是一种由人类基因LTC4S编码的[5][6]

该蛋白也简称为LTC4S(或称为谷胱苷肽S-转移酶II,英语:glutathione S-transferase II)是一种将白三烯A4谷胱甘肽结合生成白三烯C4合酶。它也是跨膜蛋白MAPEG家族的一员。

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000283887、​ENSG00000213316 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000020377 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Lam BK, Penrose JF, Freeman GJ, Austen KF. Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4. Proc Natl Acad Sci U S A. Sep 1994, 91 (16): 7663–7. PMC 44462可免费查阅. PMID 8052639. doi:10.1073/pnas.91.16.7663. 
  6. ^ Entrez Gene: LTC4S leukotriene C4 synthase. 
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白三烯C4合酶
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