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格罗·米森伯克

格罗·米森伯克
出生1965年7月15日 编辑维基数据 (58岁)
因河畔布劳瑙 编辑维基数据
就读学校
职业神经学家、大学教师 编辑维基数据
雇主
奖项InBev-Baillet Latour Health Prize、皇家学会院士、大脑奖、加贝奖、Bayliss-Starling Prize Lecture、威廉·埃克斯纳奖章、华伦·阿波特奖、科睿唯安引文桂冠奖、拉姆福德奖 编辑维基数据
网站http://www.cncb.ox.ac.uk/team/group-leaders/miesenboeck/ 编辑维基数据

格罗·米森伯克(德语:Gero Miesenböck,1965年7月15日),奥地利神经科学家,牛津大学韦恩弗雷特生理学教授、神经回路和行为学中心主任,莫德林学院研究员。[1]

生平

他从因斯布鲁克大学获医学博士学位并在詹姆斯·罗思曼指导下进行博士后研究。来牛津之前,他曾在纪念斯隆-凯特琳癌症中心耶鲁大学任职。[2][3]

米森伯克开创了现在被称为光遗传学的领域。[4][5][6][7][8]他是第一个从遗传上修改神经细胞,以使它们的电活动可以被光控制的科学家。[4]这涉及编码光敏感视蛋白的DNA的植入。米森伯克使用了类似的遗传修饰来繁殖动物。这些动物的脑包含集成到它们的神经通路中的光敏感的细胞,第一次表明了这些动物的行为可被远程控制。[5][8][9]

参考资料

  1. ^ 存档副本. [2013-10-30]. (原始内容存档于2013-11-02).  Miesenböck’s research website at the University of Oxford
  2. ^ G. Miesenböck, J. E. Rothman. Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins. Proceedings of the National Academy of Sciences of the United States of America. 1997-04-01, 94 (7): 3402–3407 [2019-02-12]. ISSN 0027-8424. PMC 20382可免费查阅. PMID 9096406. (原始内容存档于2013-11-01). 
  3. ^ G. Miesenböck, D. A. De Angelis, J. E. Rothman. Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature. 1998-07-09, 394 (6689): 192–195 [2019-02-12]. ISSN 0028-0836. PMID 9671304. doi:10.1038/28190. (原始内容存档于2019-12-05). 
  4. ^ 4.0 4.1 Boris V. Zemelman, Georgia A. Lee, Minna Ng, Gero Miesenböck. Selective photostimulation of genetically chARGed neurons. Neuron. 2002-01-03, 33 (1): 15–22 [2019-02-12]. ISSN 0896-6273. PMID 11779476. (原始内容存档于2017-03-15). 
  5. ^ 5.0 5.1 Susana Q. Lima, Gero Miesenböck. Remote control of behavior through genetically targeted photostimulation of neurons. Cell. 2005-04-08, 121 (1): 141–152 [2019-02-12]. ISSN 0092-8674. PMID 15820685. doi:10.1016/j.cell.2005.02.004. (原始内容存档于2016-07-04). 
  6. ^ Gero Miesenböck. Lighting up the brain. Scientific American. 2008-10, 299 (4): 52–59 [2019-02-12]. ISSN 0036-8733. PMID 18847085. (原始内容存档于2013-11-01). 
  7. ^ Gero Miesenböck. The optogenetic catechism. Science (New York, N.Y.). 2009-10-16, 326 (5951): 395–399 [2019-02-12]. ISSN 1095-9203. PMID 19833960. doi:10.1126/science.1174520. (原始内容存档于2013-11-01). 
  8. ^ 8.0 8.1 http://www.ted.com/talks/gero_miesenboeck.html页面存档备份,存于互联网档案馆) Miesenböck speaks at TED about optogenetics
  9. ^ Zimmer, Carl. An Off-or-On Switch for Controlling Animals?. New York Times. [12 April 2005]. 
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格罗·米森伯克
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