For faster navigation, this Iframe is preloading the Wikiwand page for 基底细胞癌.

基底细胞癌

基底细胞癌
同义词基底细胞皮肤癌、基底细胞瘤
一位老年人的鼻翼部位因基底细胞癌而出现溃烂情形
症状皮肤长出一块无痛的隆起部分,其上可能布有具光泽的蛛网纹或是溃疡[1]
风险因素肤色较浅紫外线、接受放射线疗法、长期暴露、以及免疫功能不佳[2]
诊断方法皮肤检查、活体组织切片[3]
鉴别诊断栗粒疹英语Milia脂漏性角化症英语seborrheic keratosis黑色素瘤银屑病[4]
治疗手术切除[2]
预后良好[5]
患病率约30%的白人(美国)[2]
死亡数[6]
分类和外部资源
医学专科皮肤病学肿瘤学
ICD-112C32
ICD-10C44
DiseasesDB1264
MedlinePlus000824
eMedicine276624
[编辑此条目的维基数据]

基底细胞癌(Basal-cell carcinoma,BCC)或称基底细胞瘤,是最常见的皮肤癌症英语skin cancer[2]。患者的皮肤通常会先长出一块无痛的隆起部分,其上可能布有具光泽的蛛网纹或是溃疡[1]。此种癌症的生长速度缓慢,并会损伤其周边的组织,但不太可能出现远端转移,也不太会直接导致死亡[7]

危险因子包括紫外线暴露、肤色较浅、接受放射线疗法、长期暴露、以及免疫缺陷[2]。孩童时期的紫外线暴露尤其有害[5]。近期日晒床也逐渐成为另一个常见的紫外线暴露源[8]。基底细胞癌的诊断通常奠基于皮肤检查,但确诊则需靠活体组织切片[2][3]

目前尚不清楚擦防晒油是否会影响得到基底细胞癌的风险[9]。治疗普遍是靠手术切除。如果癌症的范围很小,可能进行单纯的切除,否则一般会建议进行莫氏手术英语Mohs surgery[2]。其他治疗选项包括冷冻疗法英语Cryosurgery、局部化学疗法激光手术,或是涂抹咪喹莫特英语Imiquimod。在少数发生远端转移的案例中,也可能会使用化学治疗标靶治疗[10]

基底细胞癌至少占全球癌症总数的32%[7][11]。在非黑色素瘤的皮肤癌中,基底细胞癌至少占了80%。在美国,约有35%的白人男性和25%的白人女性在一生中曾经得过基底细胞癌[2]

参考资料

[编辑]
  1. ^ 1.0 1.1 Skin Cancer Treatment (PDQ®). NCI. 2013-10-25 [30 June 2014]. (原始内容存档于2014-07-05). 
  2. ^ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Gandhi, Sumul Ashok; Kampp, Jeremy. Skin Cancer Epidemiology, Detection, and Management. The Medical Clinics of North America. 2015-11, 99 (6) [2022-07-28]. ISSN 1557-9859. PMID 26476255. doi:10.1016/j.mcna.2015.06.002. (原始内容存档于2022-04-23). 
  3. ^ 3.0 3.1 Skin Cancer Treatment. National Cancer Institute. 21 June 2017 [2 July 2017]. (原始内容存档于2017-07-04) (英语). 
  4. ^ Krutmann, Jean; Humbert, Philippe. Nutrition for Healthy Skin: Strategies for Clinical and Cosmetic Practice. Springer Science & Business Media. 2010: 31 [2019-04-30]. ISBN 9783642122644. (原始内容存档于2017-09-10) (英语). 
  5. ^ 5.0 5.1 World Cancer Report 2014.. World Health Organization. 2014: Chapter 5.14. ISBN 9283204298. 
  6. ^ Wang, Haidong; Naghavi, Mohsen; Allen, Christine; Barber, Ryan M.; Bhutta, Zulfiqar A.; Carter, Austin; Casey, Daniel C.; Charlson, Fiona J.; Chen, Alan Zian; Coates, Matthew M.; Coggeshall, Megan. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016-10-08, 388 (10053). ISSN 0140-6736. PMC 5388903可免费查阅. PMID 27733281. doi:10.1016/S0140-6736(16)31012-1 (英语). 
  7. ^ 7.0 7.1 Cakir, Burak Ömür; Adamson, Peter; Cingi, Cemal. Epidemiology and Economic Burden of Nonmelanoma Skin Cancer. Facial Plastic Surgery Clinics of North America. Nonmelanoma Skin Cancer of the Head and Neck. 2012-11-01, 20 (4). ISSN 1064-7406. doi:10.1016/j.fsc.2012.07.004 (英语). 
  8. ^ Gallagher, Richard P.; Lee, Tim K.; Bajdik, Chris D.; Borugian, Marilyn. Ultraviolet radiation. Chronic Diseases in Canada. 2010,. 29 Suppl 1 [2022-07-28]. ISSN 1481-8523. PMID 21199599. (原始内容存档于2022-08-08). 
  9. ^ Jou, Paul C.; Feldman, Ron J.; Tomecki, Kenneth J. UV protection and sunscreens: What to tell patients. Cleveland Clinic Journal of Medicine. 2012-06-01, 79 (6) [2022-07-28]. ISSN 0891-1150. PMID 22660875. doi:10.3949/ccjm.79a.11110. (原始内容存档于2022-09-02) (英语). 
  10. ^ Skin Cancer Treatment. National Cancer Institute. 21 June 2017 [2 July 2017]. (原始内容存档于2017-07-04) (英语). 
  11. ^ Dubas, Lauren E.; Ingraffea, Adam. Nonmelanoma Skin Cancer. Facial Plastic Surgery Clinics of North America. Facial Skin: Contemporary Topics for the Surgeon. 2013-02-01, 21 (1). ISSN 1064-7406. doi:10.1016/j.fsc.2012.10.003 (英语). 

外部链接

[编辑]
{{bottomLinkPreText}} {{bottomLinkText}}
基底细胞癌
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install
{{::$root.activation.text}}

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!


Your input will affect cover photo selection, along with input from other users.

X

Get ready for Wikiwand 2.0 🎉! the new version arrives on September 1st! Don't want to wait?