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Thuốc kháng virus.
Thuốc kháng virus
Thuốc kháng retrovirus để điều trị HIV.
Thuốc kháng virus hay thuốc chống virus (tiếng Anh: Antiviral drugs) là một loại thuốc được sử dụng đặc biệt để điều trị bệnh virus nhiều hơn là các loại vi khuẩn khác.[1] Hầu hết các loại thuốc kháng virus khác đều sử dụng cho những trường hợp nhiễm virus đặc biệt, trong khi một loại thuốc kháng phổ rộng khác lại hiệu quả để điều trị một loạt các virus.[2]
^Rossignol JF (2014). “Nitazoxanide: a first-in-class broad-spectrum antiviral agent”. Antiviral Res. 110: 94–103. doi:10.1016/j.antiviral.2014.07.014. PMID25108173. Originally developed and commercialized as an antiprotozoal agent, nitazoxanide was later identified as a first-in-class broad-spectrum antiviral drug and has been repurposed for the treatment of influenza. ... From a chemical perspective, nitazoxanide is the scaffold for a new class of drugs called thiazolides. These small-molecule drugs target host-regulated processes involved in viral replication. ... A new dosage formulation of nitazoxanide is presently undergoing global Phase 3 clinical development for the treatment of influenza. Nitazoxanide inhibits a broad range of influenza A and B viruses including influenza A(pH1N1) and the avian A(H7N9) as well as viruses that are resistant to neuraminidase inhibitors. ... Nitazoxanide also inhibits the replication of a broad range of other RNA and DNA viruses including respiratory syncytial virus, parainfluenza, coronavirus, rotavirus, norovirus, hepatitis B, hepatitis C, dengue, yellow fever, Japanese encephalitis virus and human immunodeficiency virus in cell culture assays. Clinical trials have indicated a potential role for thiazolides in treating rotavirus and norovirus gastroenteritis and chronic hepatitis B and chronic hepatitis C. Ongoing and future clinical development is focused on viral respiratory infections, viral gastroenteritis and emerging infections such as dengue fever.
^Schnitzler, P; Schön, K; Reichling, J (2001). “Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture”. Die Pharmazie. 56 (4): 343–7. PMID11338678.
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