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SLC5A1

SLC5A1
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген SLC5A1[d][1]
Молекуляр функция transporter activity[d][2], связывание с белками плазмы[d][3], symporter activity[d][4], glucose:sodium symporter activity[d][2][2][5], glucose:sodium symporter activity[d][4][4][6][…] һәм transmembrane transporter activity[d][4]
Күзәнәк компоненты мембрана өлеше[d][2], мембрана[d][4][4], cell-cell junction[d][4], күзәнәк мембранасы[d][2], күзәнәк мембранасы өлеше[d][7], brush border membrane[d][4], apical plasma membrane[d][4], экзосома[d][8][9], күзәнәк мембранасы[d][4][10], мембрана өлеше[d][4][10] һәм экзосома[d][11]
Биологик процесс glucose transmembrane transport[d][2], sodium ion transport[d][2], ion transport[d][4], carbohydrate transport[d][4], трансмембранный транспорт[d][4], intestinal D-glucose absorption[d][2], intestinal hexose absorption[d][4], перенос[d][2][2], sodium ion transport[d][4][10] һәм glucose transmembrane transport[d][7][6]
Тәэсир итешә canagliflozin[d][12], dapagliflozin[d][12], empagliflozin[d][12] һәм sergliflozin etabonate[d][12]
Изображение Gene Atlas

SLC5A1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[13][14]

  1. 1,0 1,1 UniProt
  2. 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 GOA
  3. Hung M. Survival of cancer cells is maintained by EGFR independent of its kinase activity // Cancer CellCell Press, Elsevier BV, 2008. — ISSN 1535-6108; 1878-3686doi:10.1016/J.CCR.2008.03.015PMID:18455122
  4. 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 4,11 4,12 4,13 4,14 4,15 GOA
  5. Lostao M. P. Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption // Nature Genetics / M. Axton, T. FaialNPG, 1996. — ISSN 1061-4036; 1546-1718doi:10.1038/NG0296-216PMID:8563765
  6. 6,0 6,1 S Lambotte, M Veyhl, M Köhler et al. The human gene of a protein that modifies Na(+)-D-glucose co-transport // DNA and Cell Biology / J. HandelsmanMary Ann Liebert, Inc., 1996. — ISSN 1044-5498; 1557-7430; 0198-0238doi:10.1089/DNA.1996.15.769PMID:8836035
  7. 7,0 7,1 Lostao M. P. Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption // Nature Genetics / M. Axton, T. FaialNPG, 1996. — ISSN 1061-4036; 1546-1718doi:10.1038/NG0296-216PMID:8563765
  8. Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of ProteomicsElsevier BV, 2013. — ISSN 1874-3919; 0165-022Xdoi:10.1016/J.JPROT.2013.01.012PMID:23376485
  9. Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. BriggsAmerican Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450doi:10.1681/ASN.2008040406PMID:19056867
  10. 10,0 10,1 10,2 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform.OUP, 2011. — ISSN 1467-5463; 1477-4054doi:10.1093/BIB/BBR042PMID:21873635
  11. Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. BriggsAmerican Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450doi:10.1681/ASN.2008040406PMID:19056867
  12. 12,0 12,1 12,2 12,3 IUPHAR/BPS Guide to PHARMACOLOGY
  13. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  14. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Бу — аксым турында мәкалә төпчеге.Сез мәкаләне үзгәртеп һәм мәгълүмат өстәп, Википедия проектына ярдәм итә аласыз.
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SLC5A1
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