2006 MTV Video Müzik Ödülleri 31 Ağustos, 2006 tarihinde Amerika'nın New York şehrindeki Radio City Music Hall'de gerçekleştirilen ödül törenidir. Sunuculuğu, Amerikalı oyunucu ve müzisyen Jack Black üstlenmiştir.

Daha önceki ödüllerde olduğu gibi halk en iyi video, erkek sanatçı, kadın sanatçı gibi dallarda oy kullanmış; en iyi yönetmen, koreografi gibi dallar ise profesyonel jüri tarafından seçilmiştir.

• Christina Aguilera — "Ain't No Other Man"
• Madonna — "Hung Up"
• Panic! at the Disco — "I Write Sins Not Tragedies"
• Red Hot Chili Peppers — "Dani California"
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie"

• James Blunt - "You're Beautiful"
• Busta Rhymes (featuring Mary J. Blige, Rah Digga, Missy Elliott, Lloyd Banks, Papoose veDMX) — "Touch It Remix"
• Nick Lachey — "What's Left of Me"
• T.I. — "What You Know"
• Kanye West (featuring Jamie Foxx) — "Gold Digger"

• Christina Aguilera — "Ain't No Other Man"
• Kelly Clarkson — "Because of You"
• Nelly Furtado (featuring Timbaland) — "Promiscuous"
• Madonna — "Hung Up"
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie"

• The All-American Rejects — "Move Along"
• Fall Out Boy — "Dance, Dance"
• Gnarls Barkley — "Crazy"
• Panic! at the Disco — "I Write Sins Not Tragedies"
• Red Hot Chili Peppers — "Dani California"

• Angels & Airwaves — "The Adventure"
• Avenged Sevenfold — "Bat Country"
• James Blunt — "You're Beautiful"
• Chris Brown (featuring Juelz Santana) — "Run It!"
• Panic! at the Disco — "I Write Sins Not Tragedies"
• Rihanna — "SOS"

• Christina Aguilera — "Ain't No Other Man"
• Nelly Furtado (featuring Timbaland) — "Promiscuous"
• Madonna — "Hung Up"
• Pink — "Stupid Girls"
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie"

• 30 Seconds to Mars — "The Kill"
• AFI — "Miss Murder"
• Green Day — "Wake Me Up When September Ends"
• Panic! at the Disco — "I Write Sins Not Tragedies"
• Red Hot Chili Peppers — "Dani California"

• Beyoncé (featuring Slim Thug ve Bun B) — "Check on It"
• Mary J. Blige — "Be Without You"
• Chris Brown — "Yo (Excuse Me Miss)"
• Mariah Carey — "Shake It Off"
• Jamie Foxx (featuring Ludacris) — "Unpredictable"

• 50 Cent — "Window Shopper"
• Busta Rhymes (featuring Mary J. Blige, Rah Digga, Missy Elliott, Lloyd Banks, Papoose, and DMX) — "Touch It Remix"
• Chamillionaire (featuring Krayzie Bone) — "Ridin'"
• T.I. — "What You Know"
• Yung Joc (featuring Nitti) — "It's Goin' Down"

• Black Eyed Peas — "My Humps"
• Common — "Testify"
• Daddy Yankee — "Rompe"
• Three 6 Mafia (featuring Young Buck, Eightball ve MJG) — "Stay Fly"
• Kanye West (featuring Jamie Foxx) — "Gold Digger"

• Nelly Furtado (featuring Timbaland) — "Promiscuous"
• Madonna — "Hung Up"
• Sean Paul — "Temperature"
• Pussycat Dolls (featuring Snoop Dogg) — "Buttons"
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie"

• 10 Years — "Wasteland" (Yönetmen: Kevin Kerslake)
• AFI — "Miss Murder" (Yönetmen: Marc Webb)
• Common — "Testify" (Yönetmen: Anthony Mandler)
• Gnarls Barkley — "Crazy" (Yönetmen: Robert Hales)
• Red Hot Chili Peppers — "Dani California" (Yönetmen: Tony Kaye)

• Christina Aguilera — "Ain't No Other Man" (Choreographer: Jerri Slaughter)
• Madonna — "Hung Up" (Choreographer: Stephanie Roos)
• Sean Paul — "Temperature" (Choreographer: Tanisha Scott)
• Pussycat Dolls (featuring Snoop Dogg) — "Buttons" (Choreographer: Mike Mindon)
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie" (Choreographer: Shakira)

• Angels & Airwaves — "The Adventure" (Special Effects: Jack Effects)
• Beck — "Hell Yes" (Special Effects: Hammer & Tongs)
• Missy Elliott — "We Run This" (Special Effects: Louis Mackall and Tonya Wallander)
• Pearl Jam — "Life Wasted" (Special Effects: Fernando Apodaca)
• U2 — "Original of the Species" (Special Effects: John Leamy & Lawrence Nimrichter)

• 10 Years — "Wasteland" (Sanat Yönetmeni: Trae King)
• Common — "Testify" (Sanat Yönetmeni: David Ross)
• Panic! at the Disco — "I Write Sins Not Tragedies" (Sanat Yönetmeni: Lindy McMichael, Jamie Drake and Erin Wieczorek)
• Red Hot Chili Peppers — "Dani California" (Sanat Yönetmeni: Justin Dragonis)
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie" (Sanat Yönetmeni: Laura Fox)

• The All-American Rejects — "Move Along" (Editor: J.D. Smyth)
• Angels & Airwaves — "The Adventure" (Editor: Clark Eddy)
• Gnarls Barkley — "Crazy" (Editor: Ken Mowe)
• Red Hot Chili Peppers — "Dani California" (Editor: Peter Goddard)
• U2 — "Original of the Species" (Editor: Olivier Wicki)

• AFI — "Miss Murder" (Director of Photography: Wells Hackett)
• James Blunt — "You're Beautiful" (Director of Photography: Robbie Ryan)
• Prince — "Black Sweat" (Director of Photography: Checco Varese)
• Red Hot Chili Peppers — "Dani California" (Director of Photography: Tony Kaye)
• Ashlee Simpson — "Invisible" (Director of Photography: Jeff Cutter)

• Burnout Revenge (Electronic Arts)
• Driver: Parallel Lines (Atari)
• Fight Night Round 3 (Electronic Arts)
• Marc Eckō's Getting Up: Contents Under Pressure (Atari)
• NBA 2K6" (2K Games)

• Dreamfall: The Longest Journey (Composer: Leon Willett)
• Elder Scrolls IV: Oblivion (Composer: Jeremy Soule)
• Electroplankton (Composer: user generated soundtrack)
• Hitman: Blood Money (Composer: Jesper Kyd)
• Ghost Recon: Advanced Warfighter (Composer: Tom Salta)

• Black Eyed Peas — "My Humps"
• Bubba Sparxxx (featuring Ying Yang Twins) — "Ms. New Booty"
• Fort Minor (featuring Holly Brook) — "Where'd You Go"
• Nelly (featuring Paul Wall) — "Grillz"
• Kanye West (featuring Jamie Foxx) — "Gold Digger"

• 30 Seconds to Mars — "The Kill"
• Lil Wayne — "Fireman"
• Taking Back Sunday — "MakeDamnSure"
• Three 6 Mafia (featuring Young Buck, Eightball ve MJG) — "Stay Fly"
• Yung Joc (featuring Nitti) — "It's Goin' Down"

• Chris Brown (featuring Juelz Santana) — "Run It!" (10%)
• Kelly Clarkson — "Because of You" (28%)
• Fall Out Boy — "Dance, Dance" (38%)
• Rihanna — "SOS" (6%)
• Shakira (featuring Wyclef Jean) — "Hips Don't Lie" (18%)

• Hype Williams