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Enzymaktivator

Modell av fosfofruktokinas hos bakterien Bacillus stearothermophilus.

Enzymaktivatorer är molekyler som binder till enzymer och på så vis ökar deras aktivitet. Dessa molekyler är ofta involverade i allosterisk reglering av enzymer som kontrollerar metabolismen. Ett exempel på en enzymaktivator som fungerar på detta vis är fruktos-2,6-bisfosfat som aktiverar fosfofruktokinas 1 och ökar glykolysens hastighet vid närvaro av glukagon.[1][2]

  1. ^ Kurland IJ, Pilkis SJ (1 juni 1995). ”Covalent control of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: insights into autoregulation of a bifunctional enzyme”. Protein Sci. "4" (6): ss. 1023–37. doi:10.1002/pro.5560040601. PMID 7549867. PMC: 2143155. Arkiverad från originalet den 5 september 2007. https://web.archive.org/web/20070905143900/http://www.proteinscience.org/cgi/reprint/4/6/1023. 
  2. ^ Okar DA, Lange AJ (9 september 1999). ”Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes”. Biofactors "10" (1): ss. 1–14. doi:10.1002/biof.5520100101. PMID 10475585. 
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Enzymaktivator
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