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Ubikvitin C

Ubikvitin C
PDB prikaz baziran na 1aar​.
Dostupne strukture
1aar​, 1cmx​, 1d3z​, 1f9j​, 1fxt​, 1g6j​, 1gjz​, 1nbf​, 1ogw​, 1otr​, 1p3q​, 1q0w​, 1q5w​, 1s1q​, 1sif​, 1tbe​, 1ubi​, 1ubq​, 1ud7​, 1uzx​, 1v80​, 1v81​, 1wr1​, 1wr6​, 1wrd​, 1xd3​, 1xqq​, 1yd8​, 1yiw​, 1yj1​, 1yx5​, 1yx6​, 1zgu​, 2ayo​, 2bgf​, 2c7m​, 2c7n​, 2d3g​, 2den​, 2dx5​, 2fcm​, 2fcn​, 2fcq​, 2fcs​, 2fid​, 2fif​, 2fuh​, 2g3q​, 2g45​, 2gbj​, 2gbk​, 2gbm​, 2gbn​, 2gbr​, 2gmi​, 2hd5​, 2hth​, 2ibi​, 2j7q​, 2nr2​, 2o6v​, 2oob
Identifikatori
Simboli UBC; HMG20
Vanjski ID OMIM191340 MGI98889 HomoloGene39626 GeneCards: UBC Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 7316 22190
Ensembl ENSG00000150991 ENSMUSG00000008348
UniProt P0CG48 Q3TH47
RefSeq (mRNA) XM_001132949 XM_001001910
RefSeq (protein) XP_001132949 XP_001001910
Lokacija (UCSC) Chr 12:
123.96 - 123.97 Mb
Chr 5:
125.68 - 125.68 Mb
PubMed pretraga [1] [2]

Ubikvitin je protein koji je kod čoveka kodiran UBC genom.[1][2][3]

Interakcije

Za ubikvitin C je pokazano da interaguje sa SCNN1A,[4][5] SCNN1G,[4][5] Parkin (ligazom),[6][7] P70-S6 kinazom 1,[8] TRAF6,[9][10][11][12][13] HDAC3,[14] SFPQ,[15] S100A10,[16] SMAD3,[17][18] NOTCH1,[19] HIF1A,[20][21][22] receptorom epidermalnog faktora rasta,[23][24][25] E2F1,[26] Basigin,[27] IRAK1,[9][12][28][29] NFE2L2,[30][31] RIPK1,[9][13][32][33][34] Mdm2,[35][36][37] Kapa opioidnim receptorom,[38] NUAK1,[39] BIRC2,[33][40][41] tiroidnim hormonskim receptorom alfa,[14] Sp1 transkriptnim faktorom,[42] SMURF2,[43][44] MARK4,[39] Cdk1,[14] PCNA[45][46][47] i P53.[23][35][36][37][48][49][50][51]

Reference

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  3. ^ „Entrez Gene: UBC ubiquitin C”. 
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  6. ^ Yu, Furong; Jianhua, Zhou (2008). „Parkin is ubiquitinated by Nrdp1 and abrogates Nrdp1-induced oxidative stress”. Neurosci. Lett. Ireland. 440 (1): 4—8. ISSN 0304-3940. PMID 18541373. doi:10.1016/j.neulet.2008.05.052. 
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Literatura

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Ubikvitin C
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