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RNK-usmerena RNK polimeraza

RNK-usmerena RNK polimeraza
Identifikatori
EC broj2.7.7.48
CAS broj9026-28-2
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

RNK-usmerena RNK polimeraza (EC 2.7.7.48, RNK nukleotidiltransferaza (RNK-zavisna), RNK-zavisna ribonukleatna nukleotidiltransferaza, 3D polimeraza, PB1 proteini, PB2 proteini, fag f2 replikaza, polimeraza L, Q-beta replikaza, fag f2 replikaza, ribonukleinsko kiselinska replikaza, ribonukleat nukleotidiltransferaza zavisna od ribonukleinske kiseline, ribonukleinsko kiselinskaa polimeraza zavisna od ribonukleinske kiseline, ribonukleinska replikaza, ribonukleinska sintetaza, RNK replikaza, RNK sintetaza, RNK transkriptaza, RNK-zavisna ribonukleatna nukleotidiltransferaza, RDRP, RNK-zavisna RNK polimeraza, RNK-zavisna RNK replikaza, transkriptaza) je enzim sa sistematskim imenom nukleozid-trifosfat:RNK nukleotidiltransferaza (RNK-zavisna).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

nukleozid trifosfat + RNKn difosfat + RNKn+1

Ovaj enzim katalizuje RNK-šablnom usmereno produženje 3'- kraja RNK lanaca, dodajući jedan po jedan nukleotid.

  1. ^ August, J.T., Cooper, S., Shapiro, L. and Zinder, N.D. (1963). „RNA phage induced RNA polymerase”. Cold Spring Harbour Symp. Quant. Biol. 28: 95—97. 
  2. ^ Haruna, J., Nozu, K., Ohtaka, Y. and Spiegelman, S. (1963). „A'n RNA "Replicase" induced by and selective for a viral RNA: isolation and properties”. Proc. Natl. Acad. Sci. USA. 50: 905—911. 
  3. ^ Weismann, C., Simon, L. and Ochoa, S. (1963). „Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid”. Proc. Natl. Acad. Sci. USA. 49: 407—414. 

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RNK-usmerena RNK polimeraza
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