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Ekso-a-sijalidaza

Ekso-a-sijalidaza
Identifikatori
EC broj3.2.1.18
CAS broj9001-67-6
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Ekso-a-sijalidaza (EC 3.2.1.18, neuraminidaza, sijalidaza, alfa-neuraminidaza, acetilneuraminidaza) je enzim sa sistematskim imenom acetilneuraminil hidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

hidroliza alfa-(2->3)-, alfa-(2->6)-, alfa-(2->8)- glikozidnih veza terminalnih ostataka sijalinske kiseline u oligosaharidima, glikoproteinima, glikolipidima, kolominnoj kiselini i sintetičkim supstratima

Ovaj enzim ne deluje na 4-O-acetilisane sijalne kiseline.

  1. ^ Schauer, R. (1982). „Sialic acids”. Adv. Carbohydr. Chem. Biochem. 40: 131—234. PMID 6762816. 
  2. ^ Cabezas, J.A. (1991). „Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase”. Biochem. J. 278: 311—312. PMID 1883340. 

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Ekso-a-sijalidaza
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