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Laktaza

Izvor: Wikipedija

Laktaza
Tetramer laktaze (E. coli)
Identifikatori
EC broj 3.2.1.108
CAS broj 2604851
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Laktaza (EC 3.2.1.108, laktaza-florizinska hidrolaza) je enzim sa sistematskim imenom laktoza galaktohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

laktoza + H2O D-galaktoza + D-glukoza

Enzim iz intestinalne sluznice je izolovan kao kompleks koji takođe katalizuje reakciju enzima EC 3.2.1.62, glikozilkeramidaza.

Reference

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  1. Lorenz-Meyer, H., Blum, A.L., Haemmerli, H.P. and Semenza, G. (1972). „A second enzyme defect in acquired lactase deficiency: lack of small-intestinal phlorizin-hydrolase”. Eur. J. Clin. Invest. 2: 326-331. PMID 5082068. 
  2. Ramaswamay, S. and Radhakrishnan, A.N. (1975). „Lactase-phlorizin hydrolase complex from monkey small intestine. Purification, properties and evidence for two catalytic sites”. Biochim. Biophys. Acta 403: 446-455. PMID 810166. 
  3. Schlegel-Haueter, S., Hore, P., Kerry, K.R. and Semenza, G. (1972). „The preparation of lactase and glucoamylase of rat small intestine”. Biochim. Biophys. Acta 258: 506-519. PMID 5010299. 
  4. Skovbjerg, H., Norén, O., Sjöström, H., Danielsen, E.M. and Enevoldsen, B.S. (1982). „Further characterization of intestinal lactase/phlorizin hydrolase”. Biochim. Biophys. Acta 707: 89-97. PMID 6814489. 
  5. Skovbjerg, H., Sjöström, H. and Norén, O. (1981). „Purification and characterization of amphiphilic lactase-phlorizin hydrolase from human small-intestine”. Eur. J. Biochem. 114: 653-661. PMID 6786877. 
  6. Asp, N.G., Dahlqvist, A. and Koldovský, O. (1969). „Human small-intestinal β-galactosidases. Separation and characterization of one lactase and one hetero β-galactosidase”. Biochem. J. 114: 351-359. PMID 5822067. 

Literatura

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Spoljašnje veze

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Laktaza
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