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Antiserum

Antiserum er et serum som inneholder polyklonale antistoffer. Antiserum benyttes til å formidle passiv immunitet til mange sykdommer. Blodoverføring av passive antistoffer fra en tidligere overlevende, er den eneste kjente effektive behandling for Ebola-infeksjon (men med liten suksessrate).[1]

Det mest brukte antiserum for mennesker er antitoxiner eller antivenom, for å behandle envenomation.

Beskyttelse kan oppnås ved at serum fra personer som har gjennomgått en slik infeksjonsykdom overføres til personer som risikerer å bli smittet av denne sykdommen. Personer som mottar antiserum, oppnår umiddelbart beskyttelse mot den aktuelle sykdommen. Beskyttelsen varer imidlertid bare et par måneder, fordi antistoffene (IgG-antistoffer) etter hvert brytes ned.[2]

Referanser

[rediger | rediger kilde]
  1. ^ Mupapa K, Massamba M, Kibadi K, Kuvula K, Bwaka A, Kipasa M, Colebunders R, Muyembe-Tamfum JJ. 1999. Treatment of Ebola Hemorrhagic Fever with Blood Transfusions from Convalescent Patients. The Journal of Infectious Diseases 179(suppl 1):S18-23.
  2. ^ Menneskekroppen Fysiologi og anatomi,kap 11 immunforsvaret,
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Antiserum
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