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Neutrofil

Neutrophil
Gambaran 3D neutrofil
Neutrofil dengan nukleus bersegmen dikelilingi sel darah merah dan platelet. Granul intrasel dapat dilihat dalam sitoplasma (pewarna Giemsa).
Butiran
SistemSistem imun
FungsiFagositosis
Pengenalpastian
MeSHD009504
THH2.00.04.1.02012
FMAFMA:62860
Istilah anatomi mikroanatomi

Neutrofil atau neutrosit merupakan sel granulosit yang paling umum, dengan jumlah keseluruhan mencakupi 60 hingga 70 peratus dalam kalangan sel-sel darah putih dalam kebanyakan mamalia dan merupakan sel penting dalam sistem imun. Fungsi neutrofil boleh berubah mengikut mamalia.[1]

Sel neutrofil terhasil di sumsum tulang daripada sel tunjang dan membeza terhadap subpopulasi pemusnah dan perangkap. Sel-sel ini boleh memasuki bahagian yang tidak dapat dimasuki oleh sel atau molekul yang lain. Meskipun begitu, sel-sel neutrofil memiliki jangka hayat yang pendek, biasanya hanya lima hingga 90 jam sekiranya tidak diaktifkan.[2]

Neutrofil biasanya memiliki saiz 12-15 mikrometer (µm) apabila melekat pada suatu permukaan dan memiliki saiz purata 8.85 µm dalam keadaan bebas.[3]


  1. ^ Ermert D, Niemiec MJ, Röhm M, Glenthoj A, Borregard N, Urban CF (2013). "Candida albicans escapes mouse neutrophils". Journal of Leukocyte Biology. 94 (2): 223–36. doi:10.1189/jlb.0213063. PMID 23650619.
  2. ^ Tak T, Tesselaar K, Pillay J, Borghans JA, Koenderman L (2013). "What's your age again? Determination of human neutrophil half-lives revisited". Journal of Leukocyte Biology. 94 (4): 595–601. doi:10.1189/jlb.1112571. PMID 23625199.
  3. ^ Niemiec MJ, De Samber B, Garrevoet J, Vergucht E, Vekemans B, De Rycke R, Björn E, Sandblad L, Wellenreuther G, Falkenberg G, Cloetens P, Vincze L, Urban CF (2015). "Trace element landscape of resting and activated human neutrophils on sub-micrometer level". Metallomics. 7 (6): 996–1010. doi:10.1039/c4mt00346b. PMID 25832493.
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Neutrofil
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