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Apixabanum

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Apixabanum
Cognitores
ChemSpider 8358471
PubChem 10182969
DrugBank DB07828
Natura chemica
Apixabanum
Apixabanum
Formula chemica C
25
H
25
N
5
O
4
Massa molaris 459.497 g/mol
Natura pharmacologica
Codex ATC B01AF02 (WHO)
Tempus semivitae biologicum 9-14 h
Metabolismus iecore (hepaticus)
CYP3A4, CYP3A5,
CYP1A2 et al.
Excretio faecibus: 75%,
renibus: 25%
Ad usum therapeuticum
Applicatio per os
MedlinePlus a613032 (Anglice)

Apixabanum est factoris Xa inhibitor atque substantia anticoagulans in thrombosibus venosis tractandis et fibrillatione atriali[1]. Usus additus embolismorum pulmonum sive providentiae apoplexiae cerebri est.

Natura Apixabani

[recensere | fontem recensere]

Natura chemica

[recensere | fontem recensere]

Apixabanum est pyrazolopyridinum cum gregibus chemicis lactami et piperidini.

Apixabanum est substratum cytochromatis CYP3A4[2]. Massa molaris est 459.497 g/mol.

Nexus interni

  1. Granger C. B., Alexander J. H., et al. (Sep 2011). "Apixaban Versus Warfarin in Patients With Atrial Fibrillation". New England Journal of Medicine 365 (11): 981-92 
  2. Apixabani interactionum effectus (Anglice)
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Apixabanum
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