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免疫グロブリンフォールド

ヒトのフィブロネクチンに見られる免疫グロブリンフォールド

免疫グロブリンフォールド(Immunoglobulin fold)は、All-β型のタンパク質構造の1つで、7つ以下の逆平行βシートが2つのβシートによって挟み込まれた構造をしている。

基本骨格は、2つのβシート層の間を行き来する構造で、N末端側-シート1のβヘアピン-シート2のβヘアピン-シート1のβストランド-シート2のβストランド-C末端側となっている。シートの交差はx字型になり、N末端側とC末端側のヘアピンが向き合う形になる。


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免疫グロブリンフォールド
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