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Coenzima F420 idrogenasi

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coenzima F420 idrogenasi
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Numero EC1.12.98.1
ClasseOssidoreduttasi
Nome sistematico
idrogeno:coenzima F420 ossidoreduttasi
Altri nomi
idrogenasi riducente la 8-idrossi-5-deazaflavina; idrogenasi riducente F420; idrogenasi dipendente dal coenzima F420
Banche datiBRENDA, EXPASY, GTD, PDB (RCSB PDB PDBe PDBj PDBsum)
Fonte: IUBMB

La coenzima F420 idrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione:

H2 + coenzima F420 coenzima F420 ridotto

Si tratta di una flavoproteina (FAD) contenente centri ferro-zolfo e nichel. In alcuni organismi, l'enzima può contenere anche selenocisteina. L'enzima è anche in grado di ridurre l'analogo riboflavinico di F420 oltre a flavine e metilviologeno, ma in modo meno efficiente.

  • Baron, S.F. and Ferry, J.G., Purification and properties of the membrane-associated coenzyme F420-reducing hydrogenase from Methanobacterium formicicum, in J. Bacteriol., vol. 171, 1989, pp. 3846–3853, Entrez PubMed 2738024.
  • Muth, E., Morschel, E. and Klein, A., Purification and characterization of an 8-hydroxy-5-deazaflavin-reducing hydrogenase from the archaebacterium Methanococcus voltae, in Eur. J. Biochem., vol. 169, 1987, pp. 571–577, Entrez PubMed 3121317.
  • Fox, J.A., Livingston, D.J., Orme-Johnson, W.H. and Walsh, C.T., 8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization, in Biochemistry, vol. 26, 1987, pp. 4219–4228, Entrez PubMed 3663585.
  • Yamazaki, S., A selenium-containing hydrogenase from Methanococcus vannielii. Identification of the selenium moiety as a selenocysteine residue, in J. Biol. Chem., vol. 257, 1982, pp. 7926–7929, Entrez PubMed 6211447.
  • Adams, M.W.W., Mortenson, L.E. and Chen, J.-S., Hydrogenase, in Biochim. Biophys. Acta, vol. 594, 1981, pp. 105–176.
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Coenzima F420 idrogenasi
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