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CD11a

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Antigene CD11a
Gene
HUGOITGAL CD11A
LocusChr. 16 p13.1-p11
Proteina
OMIM153370
UniProtP20701

La glicoproteina CD11a è una proteina di membrana di 180 kDa presente su precursori dei macrofagi, granulociti, linfociti[1].

È una delle subunità che associandosi a CD18 forma LFA-1 molecola di adesione che riconosce ICAM-1[1][2].

È anche conosciuta come LFA-1 α (lymphocyte function-associated antigen 1, catena α)[1].

  1. ^ a b c ITGAL integrin subunit alpha L [Homo sapiens (human)] - Gene - NCBI, su www.ncbi.nlm.nih.gov. URL consultato il 26 giugno 2024.
  2. ^ (EN) Helena Yusuf-Makagiansar, Irwan T Makagiansar e Yongbo Hu, Synergistic inhibitory activity of α- and β-LFA-1 peptides on LFA-1/ICAM-1 interaction, in Peptides, vol. 22, n. 12, 2001-12, pp. 1955–1962, DOI:10.1016/S0196-9781(01)00546-0. URL consultato il 26 giugno 2024.
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CD11a
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