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Protein SREB

Protein SREB (bahasa Inggris: Sterol regulatory element binding protein, SREBP) merupakan protein yang memiliki berkas genetik SREBP1 yang terletak pada kromosom 17p11.2 dengan ekspresi defisiensi berupa sindrom Smith-Magenis,[1] dan berkas SREBP2 pada kromosom 22q13.[2] Dengan adanya kolesterol di dalam sel, SREBP akan terikat oleh SCAP,[3] dan bermigrasi dari retikulum endoplasma menuju Golgi untuk diaktivasi dengan enzim protease agar dapat menjalankan fungsinya sebagai regulator biosintesis sterol.

  1. ^ (Inggris) "SREBF1 sterol regulatory element binding transcription factor 1 [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-12-12. 
  2. ^ (Inggris) "SREBF2 sterol regulatory element binding transcription factor 2 [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-12-12. 
  3. ^ (Inggris) "SCAP SREBF chaperone [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-12-12. 



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Protein SREB
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