Nikardipin
| |
|---|---|
| Nama sistematis (IUPAC) | |
| 2-[benzyl(methyl)amino]ethylmethyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | |
| Data klinis | |
| Nama dagang | Cardene |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a695032 |
| Kat. kehamilan | ? |
| Status hukum | ℞ Preskripsi saja |
| Rute | Oral, intravenous |
| Data farmakokinetik | |
| Ikatan protein | >95% |
| Waktu paruh | 8.6 hours |
| Pengenal | |
| Nomor CAS | 55985-32-5 
|
| Kode ATC | C08CA04 |
| PubChem | CID 4474 |
| Ligan IUPHAR | 2559 |
| DrugBank | DB00622 |
| ChemSpider | 4319
|
| UNII | CZ5312222S
|
| KEGG | D08270
|
| ChEBI | CHEBI:7550 |
| ChEMBL | CHEMBL1484
|
| Data kimia | |
| Rumus | C26H29N3O6 |
| SMILES | eMolecules & PubChem |
| |
| Data fisik | |
| Titik lebur | 136-138 °C (-80 °F) |
Nikardipin adalah obat golongan antagonis kalsium dengan efek vasodilatasi. Obat ini digunakan digunakan untuk terapi krisis hipertensi melalui jalur intravena. Efek inotropik menjadi hal negatif obat nikardipin, kejadian ini juga dilaporkan minimal disebabkan obat ini lebih selektif bekerja pada otot-otot polos pembuluh darah daripada otot jantung.[1]
Referensi
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