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Togaviridae.
Togavirusi |
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Slika Rubela virusa transmisijskim elektronskim mikroskopom. |
Klasifikacija virusa |
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Skupina virusa: | Riboviria |
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Carstvo: | Orthornavirae
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Koljeno: | Kitrinoviricota
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Razred: | Alsuviricetes
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Red: | Martellivirales
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Porodica: | Togaviridae
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Rod |
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Baze podataka |
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Togaviridae su porodica virusa, u koju ubrajamo dva roda virusa:
- rod Alphavirus: npr. virus istočnog konjskog encefalitisa, virus zapadnog konjskog encefalitisa, virus venecuelanskog konjskog encefalitisa, virus rijeke Ross
- rod Rubivirus: jedini pripadnik Rubella virus
Togavirusi pripadaju IV grupi virusa prema Baltimorskoj klasifikaciji. Genom im je jednolačana pozitivna RNK duga 10,000-12,000 nukleotida. Promjer viriona je oko 70 nm, kubične je simetrije s lipoproteinskim omotačem koji sadrži glikoproteinske peplomere. Replikacija je u citoplazmi a ćeliju napuštaju pupljenjem kroz ćelijsku membranu. Virusi ove porodice su osjetljivi na povišenu temperaturu, organske rastvarače i nisku pH vrijednost. Infekcija kod čovjeka je citolitičkog tipa i dovodi do prekida sinteze ćelijskih makromolekula. Široko su rasprostranjeni.
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