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Hydroxypyruvate réductase

L'hydroxypyruvate réductase (HPR) est une oxydoréductase qui catalyse les réactions :

hydroxypyruvate + NADH + H+    D-glycérate + NAD+ ;
hydroxypyruvate + NADPH + H+    D-glycérate + NADP+.

Cette enzyme intervient notamment chez les plantes dans la photorespiration au sein des peroxysomes.

Notes et références

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  • (en) Kleczkowski LA and Edwards GE, « Identification of hydroxypyruvate and glyoxylate reductases in maize leaves », Plant Physiol., vol. 91,‎ , p. 278–286 (DOI 10.1104/pp.91.1.278)
  • (en) Kleczkowski LA, Randall DD, « Purification and characterization of a novel NADPH(NADH)-dependent hydroxypyruvate reductase from spinach leaves. Comparison of immunological properties of leaf hydroxypyruvate reductases », Biochem. J., vol. 250, no 1,‎ , p. 145–52 (PMID 3281657, PMCID 1148826)
  • (en) Kohn LD, Jakoby WB, « Tartaric acid metabolism. VII. Crystalline hydroxypyruvate reductase (D-glycerate dehydrogenase) », J. Biol. Chem., vol. 243, no 10,‎ , p. 2494–9 (PMID 4385077)
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Hydroxypyruvate réductase
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