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Somatopausia

La somatopausia es la disminución progresiva de los niveles de la hormona del crecimiento (GH) y el factor de crecimiento similar a la insulina 1 (IGF-1), hormonas del eje hipotalámico-hipofisario-somatotrópico (eje HPS), con la edad.[1]​ La secreción de GH puede ser solo el 60% de la de un adulto joven a los 70 años.[2]​ La somatopausia produce cambios en el cuerpo, como cambios en la composición corporal, como una disminución de la masa corporal magra.[1]​ Los estrógenos y la progesterona pueden oponerse a la somatopausia aumentando los niveles de GH e IGF-1.[1]

Referencias

[editar]
  1. a b c J. Larry Jameson; Leslie J. De Groot (25 de febrero de 2015). Endocrinology: Adult and Pediatric E-Book. Elsevier Health Sciences. pp. 2315-. ISBN 978-0-323-32195-2. 
  2. Roy G. Smith; Michael O. Thorner (28 de enero de 2000). Human Growth Hormone: Research and Clinical Practice. Springer Science & Business Media. pp. 325-. ISBN 978-1-59259-015-5. 
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Somatopausia
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