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MED16

Receptor de hormona tiroidea asociado a la proteína 5
Estructuras disponibles
PDB Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos THRAP5 (HGNC: 11796) DRIP92, MED16, TRAP95
Identificadores
externos
Locus Cr. 19 p13.3-17q12
Ortólogos
Especies
Humano Ratón
Entrez
10025
UniProt
Q9Y2X0 n/a
RefSeq
(ARNm)
XP_001130102 n/a

La proteína mediadora de la transcripción de la subunidad 16 de la ARN polimerasa (MED16) es una enzima que, en humanos, es codificada por el gen med16.[1][2][3]​ La proteína MED16 está implicada en la regulación de la expresión de la subunidad 16S de la ARN polimerasa.

Interacciones

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La proteína MED16 ha demostrado ser capaz de interaccionar con:

Referencias

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  1. Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Naar AM, Erdjument-Bromage H, Tempst P, Freedman LP (Jun de 1999). «Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex». Nature 398 (6730): 824-8. PMID 10235266. doi:10.1038/19783. 
  2. a b c Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J, Roeder RG (Apr de 1999). «Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators». Mol Cell (EE. UU.) 3 (3): 361-70. ISSN 1097-2765. PMID 10198638. 
  3. «Entrez Gene: THRAP5 thyroid hormone receptor associated protein 5». 
  4. a b Kang, Yun Kyoung; Guermah Mohamed, Yuan Chao-Xing, Roeder Robert G (Mar. de 2002). «The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro». Proc. Natl. Acad. Sci. U.S.A. (United States) 99 (5): 2642-7. ISSN 0027-8424. PMID 11867769. doi:10.1073/pnas.261715899. 

Enlaces externos

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MED16
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