UK-414,495

Identifiers
IUPAC name (2R)-2-({1-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclopentyl}methyl)pentanoic acid
CAS Number	337962-93-3 Y
PubChem CID	9949799
ChemSpider	8125410 N
UNII	JV29CG9MQ2
ChEMBL	ChEMBL378763 N
CompTox Dashboard (EPA)	DTXSID10432050
Chemical and physical data
Formula	C16H25N3O3S
Molar mass	339.45 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC[C@H](CC1(CCCC1)C(=O)NC2=NN=C(S2)CC)C(=O)O
InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1 N Key:FWXXCSISWQQOGS-LLVKDONJSA-N N
NY (what is this?)  (verify)

UK-414,495 is a drug developed by Pfizer for the treatment of female sexual arousal disorder. UK-414,495 acts as a potent, selective inhibitor of the enzyme neutral endopeptidase, which normally serves to break down the neuropeptide VIP. The consequent increase in VIP activity alters blood flow to the genital region leading to increased lubrication and muscle relaxation.^[1][2][3]