Transient neonatal diabetes
| Transient neonatal diabetes | |
|---|---|
 | |
| Transient neonatal diabetes mellitus is inherited in an autosomal dominant manner[1] | |
| Specialty | Pediatrics  |
Transient neonatal diabetes mellitus (TNDM) is a form of neonatal diabetes presenting at birth that is not permanent. This disease is considered to be a type of maturity onset diabetes of the young (MODY).
Types
| Type | OMIM | Gene | Locus | Description |
|---|---|---|---|---|
| TNDM1 | 601410 | ZFP57, PLAGL1 | 6p22.1, 6q24.2 | |
| TNDM2 | 610374 | ABCC8 | 11p15.1 | Due to the mutations of the other subunit of the KATP channel, SUR1, which is encoded by the ABCC8 gene.[2] |
| TNDM3 | 610582 | KCNJ11 | 11p15.1 |
Cause
This condition has to do with genetics and is often associated with having an added Chromosome 7 gene (mostly from the paternal side).[citation needed]
The form on chromosome 6 can involve imprinting.[3][4]
Diagnosis
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Management
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