Stollé synthesis
The Stollé synthesis is a series of chemical reactions that produce oxindoles from anilines and α-haloacid chlorides (or oxalyl chloride).[1][2][3][4]
![The Stollé synthesis](https://upload.wikimedia.org/wikipedia/commons/thumb/4/40/Stolle_Synthesis_Scheme.png/500px-Stolle_Synthesis_Scheme.png)
The first step is an amide coupling, while the second step is a Friedel–Crafts reaction.[5][6] An improved procedure has been developed.[7][8]
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