St. Francis or Saint Francis may refer to:

• Francis of Assisi (1181–1226), Italian founder of the Order of Friars Minor (Franciscans)
• Francis of Paola (1416–1507), Italian (Calabrian) founder of the Order of the Minims
• Francis Xavier (1506–1552), Navarrese Catholic missionary to India; co-founder of the Society of Jesus (Jesuits)
• Francis Borgia (1510–1572), Spanish Jesuit priest; third leader of the Jesuits
• Francis Solanus (1549–1610), Spanish Franciscan missionary to South America
• Francis Caracciolo (1563–1608), Italian priest who co-founded the Congregation of the Minor Clerics Regular
• Francis de Sales (1567–1622), French born bishop of Geneva, Switzerland
• Francis Ferdinand de Capillas (1607–1648), Castilian Dominican missionary; first Roman Catholic martyr killed in China
• Francis de Geronimo (1642–1716), Italian Jesuit priest
• Francis Marto (1908–1919), Portuguese Marian child visionary

• St Francis Island, an island in South Australia

• St. Francis, Alberta
• Saint-François Parish, New Brunswick, formerly named St. Francis Parish
• Saint-François-de-Madawaska, New Brunswick, formerly named St. Francis
• St. Francis Harbour, Nova Scotia

• St Francis Bay, a village in Cacadu District Municipality, Eastern Cape province
• Cape St. Francis, a town in Eastern Cape province

• St. Francis, Arkansas
• St. Francis, Florida, a ghost town in Florida
• St. Francis, Kansas
• Saint Francis, Kentucky
• St. Francis, Maine
• St. Francis, Minnesota, Anoka County
• St. Francis, Stearns County, Minnesota
• St. Francis, South Dakota, a town on the Rosebud Indian Reservation in Todd County
• St. Francis, Texas
• St. Francis, Wisconsin
• St. Francis River, a river in Missouri and Arkansas

• St. Francis College, a college in Brooklyn Heights, New York
  • St. Francis Brooklyn Terriers, the school's athletic program
• St. Francis' College, a college in Lucknow, India
• Saint Francis University (Pennsylvania), a university in Loretto, Pennsylvania
  • Saint Francis Red Flash, the school's athletic program
• Saint Francis University (Hong Kong), a university in Hong Kong formerly known as Caritas Institute of Higher Education
• St. Francis Xavier University, a university in Antigonish, Nova Scotia, Canada
• University of St. Francis, a university with locations throughout the United States
• University of Saint Francis (disambiguation), various universities
• Saint Francis High School (disambiguation), various high schools
• St. Francis Xavier High School (disambiguation), various high schools
• St. Francis' Canossian College, a secondary school in Hong Kong
• St. Francis' Canossian School, a primary school in Hong Kong
• St. Francis Xavier's College, a secondary boys' school in Hong Kong.

• St. Francis (film), a 2002 film starring Raoul Bove
• HMCS St. Francis, a Royal Canadian Navy destroyer during World War II
• St. Francis (fireboat), operated by the San Francisco Fire Department
• St. Francis Yacht Club, a sailing club in San Francisco since 2016
• St Francis F.C., a football club in Ireland
• Nobilissima Visione, a 1938 ballet by Paul Hindemith, known at its New York performance as Saint Francis
• Convent of Saint Francis (Vitoria-Gasteiz), a former convent in Basque Country, Spain
• Feast of Saint Francis, a religious and civil celebration annually held in Italy and other locations
• OSF Saint Francis Medical Center, a level I trauma center and teaching hospital in Peoria, Illinois

• St. Frances (disambiguation)
• List of places named after Saint Francis
• San Francisco, a city and county in California
• St. Francis Hospital (disambiguation)
• St. Francis in Ecstasy (disambiguation)
• Saint-François (disambiguation)
• Francis (disambiguation)
• San Francisco (disambiguation)
• San Francisco Cathedral (disambiguation)
• São Francisco (disambiguation)

This disambiguation page lists articles associated with the title St. Francis.
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