SLC22A13
Identifiers
Aliases	SLC22A13, OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3, solute carrier family 22 member 13
External IDs	OMIM: 604047; MGI: 2143107; HomoloGene: 3140; GeneCards: SLC22A13; OMA:SLC22A13 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p22.2 Start 38,265,812 bp[1] End 38,278,757 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F3 Start 119,022,040 bp[2] End 119,038,164 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in renal cortex stromal cell of endometrium metanephros human kidney apex of heart muscle of thigh blood mucosa of transverse colon cerebellum cerebellar cortex Top expressed in right kidney human kidney proximal tubule proximal straight tubule morula ganglion of vagus nerve thyroid gland embryo Convoluted tubule blastocyst More reference expression data BioGPS n/a
Gene ontology Molecular function transmembrane transporter activity organic cation transmembrane transporter activity nicotinate transmembrane transporter activity inorganic anion exchanger activity sodium-independent organic anion transmembrane transporter activity Cellular component integral component of plasma membrane apical plasma membrane membrane extracellular exosome integral component of membrane plasma membrane Biological process nicotinate transport transmembrane transport urate transport organic cation transport NAD biosynthesis via nicotinamide riboside salvage pathway inorganic anion transport sodium-independent organic anion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9390 102570 Ensembl ENSG00000172940 ENSMUSG00000074028 UniProt Q9Y226 Q6A4L0 RefSeq (mRNA) NM_004256 NM_133980 RefSeq (protein) NP_004247 NP_598741 Location (UCSC) Chr 3: 38.27 – 38.28 Mb Chr 9: 119.02 – 119.04 Mb PubMed search [3] [4]
Wikidata
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Solute carrier family 22 member 13 is a protein that in humans is encoded by the SLC22A13 gene. ^[5]

Function

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.