Promegapoietin
Drug given during chemotherapy to increase blood cell regeneration
Promegapoietin is a drug given during chemotherapy to increase blood cell regeneration. It is a colony-stimulating factor that stimulates megakaryocyte production.[1][2]
It functions by stimulating ligands for interleukin 3 and c-Mpl.[3]
- ^ Kratz-Albers K, Scheding S, Möhle R, Bühring H, Baum C, Mc Kearn J, Büchner T, Kanz L, Brugger W (2000). "Effective ex vivo generation of megakaryocytic cells from mobilized peripheral blood CD34(+) cells with stem cell factor and promegapoietin". Exp Hematol. 28 (3): 335–46. doi:10.1016/S0301-472X(99)00152-6. PMID 10720698.
- ^ Definition of promegapoietin – NCI Dictionary of Cancer Terms
- ^ Doshi P, Giri J, Abegg A, Favara J, Huynh M, Kahn L, Minnerly J, Pegg L, Villani-Price D, Siegel N, Staten N, Thomas J, McKearn J, Smith W (2001). "Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways". Exp Hematol. 29 (10): 1177–84. doi:10.1016/S0301-472X(01)00694-4. PMID 11602319.
- promegapoietin-1a at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Cytokine receptor modulators
Interleukin receptor modulators
| IL-1 |
| ||||
|---|---|---|---|---|---|
| IL-2 |
| ||||
| IL-3 |
| ||||
| IL-4 |
| ||||
| IL-5 |
| ||||
| IL-6 |
| ||||
| IL-7 |
| ||||
| IL-8 |
| ||||
| IL-9 |
| ||||
| IL-10 |
| ||||
| IL-11 |
| ||||
| IL-12 |
| ||||
| IL-13 |
| ||||
| IL-15 |
| ||||
| IL-17 |
| ||||
| IL-18 |
| ||||
| IL-20 |
| ||||
| IL-21 |
| ||||
| IL-22 |
| ||||
| IL-23 |
| ||||
| IL-27 |
| ||||
| IL-28 |
| ||||
| IL-31 |
| ||||
| IL1RL1 |
| ||||
| IL1RL2 |
| ||||
| Others |
| ||||
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.
Cover photo is available under {{::mainImage.info.license.name || 'Unknown'}} license.
Cover photo is available under {{::mainImage.info.license.name || 'Unknown'}} license.
Credit:
(see original file).
