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Mofebutazone

Mofebutazone
Clinical data
ATC code
Identifiers
  • 4-butyl-1-phenylpyrazolidine-3,5-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.016.947 Edit this at Wikidata
Chemical and physical data
FormulaC13H16N2O2
Molar mass232.283 g·mol−1
3D model (JSmol)
  • CCCCC1C(=O)NN(C1=O)c2ccccc2
  • InChI=1S/C13H16N2O2/c1-2-3-9-11-12(16)14-15(13(11)17)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3,(H,14,16) ☒N
  • Key:REOJLIXKJWXUGB-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Mofebutazone (or monophenylbutazone) is a drug used for joint and muscular pain.[1][2] It is a 3,5-pyrazolinedione derivative.

The drug binds to plasma albumin and competes with drugs such as coumarin anticoagulants, indomethacin and glucocorticoids.

References

  1. ^ Kassem MA, Schulte KE (1984-07-01). "Pharmacokinetics of [4-14C] mofebutazone after oral administration in man". European Journal of Drug Metabolism and Pharmacokinetics. 9 (3): 223–227. doi:10.1007/BF03189645. PMID 6519123. S2CID 10985688.
  2. ^ Paradies HH (December 1987). "Structure of phenylbutazone and mofebutazone in the crystalline state and in solution". Journal of Pharmaceutical Sciences. 76 (12): 920–929. doi:10.1002/jps.2600761217. PMID 3440938.
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Mofebutazone
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