This is a list of mayors of the City of Williamsport, in the U.S. state of Pennsylvania, from 1866–present.

• Maj. James M. Wood, 1866–1867
• Dr. William F. Logan, 1867–1869
• Peter Herdic, 1869–1870
• Maj. James H. Perkins, 1870–1872
• Seth W. Starkweather, 1872–1874
• Martin Powell, 1874–1876
• Seth W. Starkweather, 1876–1878
• Henry C. Parsons, 1882–1884
• Samuel M. Crans, 1884–1886
• William N. Jones, 1886–1888
• James S. Foresman, 1888–1890
• Frederick H. Keller, 1890–1893
• William G. Elliot, 1893–1896
• James Mansel, 1896–1899
• Samuel N. Williams, 1899–1902
• John F. Laedlein, 1902–1905
• Seth T. Foresman, 1905–1908
• Charles D. Wolfe, 1908–1911
• Samuel Stabler, 1911–1916
• Jonas Fischer, 1916–1917
• Archibald M. Hoagland, 1917–1924
• Hugh Gilmore, 1924–1928
• Herbert T. Ames, 1928–1932
• George K. Harris, 1932–1936
• Charles D. Wolfe, 1936–1940
• Leo C. Williamson, 1940–1952
• Clifford L. Harman, 1952–1956
• Thomas H. Levering, 1956–1964
• Raymond M. Knaur, 1964–1968
• Richard J. Carey, 1968–1972
• John R. Coder, 1972–1976
• Daniel P. Kirby, 1976–1980
• Stephen J. Lucasi, 1980–1988
• Jessica L. Bloom, 1988–1992 – First female mayor. Bloom was a former member of City Council. Was the chairwoman of Lycoming County Democratic Party until her death in 2023.
• Phillip E. Preziosi, 1992–1996 – Former member of City Police Department. Second officer to win mayor's office.
• Steven W. Cappelli, 1996–2000 – Resigned to become State Representative from 83rd legislative district, 2001–2009
• Michael R. Rafferty, 2000–2004 – Served nine years on City Council, six years as council president.
• Mary B. Wolf, 2004–2008 – Second female mayor. Wolf was a former member of City Council and a former college professor.
• Gabriel J. Campana, 2008–2020
• Derek Slaughter, 2020 – first African-American male Democratic mayor. Slaughter was a former school teacher.

• Official City of Williamsport website