Lucanthone
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| ECHA InfoCard | 100.006.849 |
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| Formula | C20H24N2OS |
| Molar mass | 340.49 g·mol−1 |
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Lucanthone is a drug used to treat parasitic diseases such as bilharziasis[1] and schistosomiasis[2] It is a prodrug and is converted to the active metabolite hycanthone.[3]
Mechanism of action
Hycanthone binds to acetylcholine receptors in the worm[4] and results in increased sensitivity to stimulation by 5-HT causing increase in motility, paired worms are separated and reproduction is stopped. It causes damage of the integument and vitelline duct.
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