This is a list of alumni of the University of Karachi.

A

• Jamiluddin Aali – Urdu poet, critic, playwright, essayist, columnist, and scholar
• Manzoor Ahmad – philosopher
• Rukhsana Ahmad – writer, playwright, and translator^[1]
• Afaq Ahmed – leader of Mohajir Qaumi Movement Pakistan
• Israr Ahmed – Pakistan-based Muslim religious figure
• Riaz Ahsan – professor and former president of Sindh Professors and Lecturers Association
• Mohammed Ajeeb – former Lord Mayor of Bradford
• Munir Akram – former Pakistan ambassador to the United Nations
• Ahmed Ali – co-founder of Progressive Writers Movement & Association; novelist; short story writer; critic; translator; diplomat; scholar
• Sohail Aman – Chief of Air Staff of the Pakistan Air Force
• Zafar Ishaq Ansari – scholar of Islamic studies
• Moinuddin Aqeel – author, critic, linguist, scholar of Urdu literature and linguistics
• Shakil Auj – Scholar of Islamic Studies and founder of Al-Tafseer Welfare Trust
• Shaukat Aziz – former Prime Minister of Pakistan; former Citibank executive officer

B

• Wali Khan Babar – GEO News journalist
• Anmol Baloch – television actress and model
• Sanam Baloch – television actress
• Ansar Burney – human rights and civil rights activist

D

• Noon Meem Danish – poet^[2]
• Joseph R. D'Cruz – professor of strategic management at the University of Toronto's Rotman School of Management^[3]
• Quentin D'Silva – former chairman and chief executive, Shell Pakistan Limited

F

• Aslam Farrukhi – Urdu author, critic, poet, linguist, scholar and broadcaster
• Tarek Fateh – writer, novelist, columnist, author
• Farman Fatehpuri – author, researcher, critic, linguist and scholar of Urdu literature and linguistics

G

• Khalida Ghous – scholar of international relations and human rights; activist

H

• Husain Haqqani – Pakistan's ambassador to the United States
• Hussain Haroon – Pakistan's ambassador to the United Nations
• Abrar Hasan – lawyer and constitutional expert
• Masuma Hasan – first female Ph.D. and first female Federal Secretary of Pakistan
• Syed Munawar Hasan – Ameer, Jamaat-e-Islami Pakistan
• Nehal Hashmi – Senator, General secretary PML-N Sindh
• Mehwish Hayat – model
• Zahida Hina – columnist, author, poet
• Abdul Rasheed Hussain – Maldivian politician and public figure
• Altaf Hussain – leader and founder of the Muttahida Qaumi Movement

I

• Ibn-e-Insha – Urdu poet humorist and travelogue writer

J

• Jameel Jalibi – linguist, critic, writer, researcher, educationist and scholar of Urdu literature
• Nasreen Jalil – Naib Nazima of Karachi; MQM leader
• Sana Javed – actress and model, best known for blockbuster drama Khaani

K

• Abul Khair Kashfi – author, researcher, critic, linguist and scholar of Urdu literature and linguistics
• Hiroji Kataoka – scholar of Urdu in Japan; exchange student in the early 1970s^[4]
• Abdul Qadeer Khan – scientist and metallurgical engineer, widely regarded as the founder of the uranium program of the country's atomic bomb projects
• Makhdoom Ali Khan – former Attorney General of Pakistan
• Rana Muhammad Akram Khan – former chairman, Punjab Bar Council

L

• Anthony Theodore Lobo – Roman Catholic bishop

M

• Rehman Malik – senator, Minister of Interior, Government of Pakistan
• A. C. Matin – microbiologist and immunologist
• Nisar Memon – former Federal Minister for Information and Broadcasting
• Ajmal Mian – former Chief Justice of Pakistan
• Haseena Moin – playwright, drama writer
• Gholam Mujtaba – politician and Pakistani American
• Waheed Murad – film actor

N

• Farooq Naek – Chairman of the Senate of Pakistan, ex-Law Minister
• Abdul Hameed Nayyar – physicist, peace activist
• Michael Nazir-Ali – Bishop of Rochester in the Church of England
• Asif Noorani – newspaper and television writer

P

• Zinia Pinto – principal of the elite St Joseph's Convent School (Karachi) from 1963 to 1999^[5]

Q

• Muhammad Ahmed Qadri – Islamic scholar and political scientist, founder of Islamic Educational and Cultural Research Center
• Pirzada Qasim – scholar, Urdu poet and Vice Chancellor of the University of Karachi

R

• Raza Rabbani – senator
• Atta ur Rahman – chairman of HEC; director of H.E.J. Research Institute of Chemistry
• Raheel Raza – author
• Nisha Rao – lawyer and activist

S

• Arman Sabir – BBC and Dawn journalist
• Faisal Sabzwari – deputy parliamentary leader of MQM
• Nida Sameer – anchorperson of Geo News
• Syed Sajjad Ali Shah – former Chief Justice of Pakistan
• Rashid Minhas Shaheed – PAF Officer; received Nishan-e-Haider
• Parveen Shakir – Urdu poet, teacher, civil servant of the Government of Pakistan
• Bina Shaheen Siddiqui
• Muhammad Ali Siddiqui – philosopher and critic
• Naweed Syed - inventor of the neurochip
• Nazim Hussain Siddiqui – former Chief Justice of Pakistan
• Saeeduzzaman Siddiqui – former Chief Justice of Pakistan
• Shahid Aziz Siddiqi – former Federal Secretary, Vice Chancellor Ziauddin University
• Takeshi Suzuki – professor of Urdu in Japan, exchange student from 1960 to 1962^[6]

T

• Atif Tauqeer – journalist, poet, writer and vlogger

U

• Muhammad Taqi Usmani – Hanafi Islamic scholar; served as a judge on the Shariah Appellate Bench of the Supreme Court of Pakistan

W

• Fauzia Wahab – politician in the Pakistan Peoples Party
• Raees Warsi – poet; author; founder and president of Urdu Markaz New York

Z

• Muhammad Ziauddin – Pakistani journalist, economist and historian