LRP3

LRP3
Identifiers
Aliases	LRP3, LDL receptor related protein 3
External IDs	OMIM: 603159; MGI: 3584516; HomoloGene: 1745; GeneCards: LRP3; OMA:LRP3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	33,208,864 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	34,914,923 bp
RNA expression pattern
	Top expressed in
	putamen; ; nucleus accumbens; ; caudate nucleus; ; left ovary; ; superior frontal gyrus; ; temporal lobe; ; right frontal lobe; ; amygdala; ; primary visual cortex; ; prefrontal cortex;
	Top expressed in
	primary visual cortex; ; superior frontal gyrus; ; ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; genital tubercle; ; ganglionic eminence; ; right kidney; ; tail of embryo; ; neural layer of retina;
	More reference expression data
	n/a
Orthologs
	4037
	435965
	ENSG00000130881
	ENSMUSG00000001802
	O75074
	n/a
	NM_002333
	NM_001024707
	NP_002324
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Low density lipoprotein receptor-related protein 3 (LRP-3) is a protein that in humans is encoded by the LRP3 gene.^[5]

References

Takatsu H, Katoh Y, Shiba Y, Nakayama K (Jul 2001). "Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains". The Journal of Biological Chemistry. 276 (30): 28541–5. doi:10.1074/jbc.C100218200. PMID 11390366.
Korenberg JR, Argraves KM, Chen XN, Tran H, Strickland DK, Argraves WS (Jul 1994). "Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1)". Genomics. 22 (1): 88–93. doi:10.1006/geno.1994.1348. PMID 7959795.
Ishii H, Kim DH, Fujita T, Endo Y, Saeki S, Yamamoto TT (Jul 1998). "cDNA cloning of a new low-density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-q13. 2". Genomics. 51 (1): 132–5. doi:10.1006/geno.1998.5339. PMID 9693042.

v t e Lipids: lipoprotein particle metabolism
Lipoprotein particle classes and subclasses	delivery of TGs: Chylomicron VLDL delivery of C and CE: IDL LDL lb LDL sd LDL Lp(a) HDL Remnant cholesterol
Apolipoproteins	APOA 1 2 4 5 APOB APOC 1 2 3 4 APOD APOE APOH SAA SAA1
Extracellular enzymes	LCAT LIPC LPL
Lipid transfer proteins	CETP MTTP PLTP
Cell surface receptors	HDL: SCARB1 IDL: LRP LRP1 LRP1B LRP2 LRP3 LRP4 LRP5 LRP5L LRP6 LRP8 LRP10 LRP11 LRP12 LDL: LDLR LRPAP1
ATP-binding cassette transporter	ABCA1 ABCG5 ABCG8