IgA pemphigus
| IgA pemphigus | |
|---|---|
 | |
| Schematic of immunoglobulin A dimer showing H-chain (blue), L-chain (red), J-chain (magenta) and secretory component (yellow). | |
| Specialty | Dermatology |
IgA pemphigus is a subtype of pemphigus with two distinct forms:
- Subcorneal pustular dermatosis (also known as Sneddon–Wilkinson disease and pustulosis subcornealis)[1] is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils.[2][3]: 203 This is distinct from and not to be confused with subcorneal pustular dermatosis type of IgA pemphigus. Sneddon's syndrome, also known as Ehrmann-Sneddon syndrome, is also a different syndrome.[4]
- Intraepidermal neutrophilic IgA dermatosis is characterized histologically by intraepidermal bullae with neutrophils, some eosinophils, and acantholysis.[3]: 465
History
Early descriptions were made by Darrell Wilkinson, a British dermatologist.[5]
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.
Cover photo is available under {{::mainImage.info.license.name || 'Unknown'}} license.
Cover photo is available under {{::mainImage.info.license.name || 'Unknown'}} license.
Credit:
(see original file).
