HLA-B78
major histocompatibility complex (human), class I, B78
| ||
| Alleles | B*7801 B*7802 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*7801 | |
| EBI-HLA | B*7802 | |
| Locus | chr.6 6p21.31 | |
HLA-B78 (B78) is an HLA-B serotype. The serotype identifies the more common HLA-B*78 gene products.[1] B78 is more common in West and North Africa, but is also scattered at low frequencies in parts of Asia. (For terminology help see: HLA-serotype tutorial)
Serotype
[edit]| B*78 | B78 | other | Sample |
| allele | % | % | size (N) |
| 7801 | 41 | 48 | 210 |
Allele frequencies
[edit]| freq | ||
| ref. | Population | (%) |
| [3] | Fulani (Burkina Faso) | 8.2 |
| [3] | Bandiagara (Mali) | 6.9 |
| [3] | Niokholo Mandinka (Senegal) | 5.3 |
| [3] | Mossi (Burkina Faso) | 2.8 |
| [3] | Guinea Bissau | 2.3 |
| [3] | Akan Adiopodoume (Ivory Coast) | 2.3 |
| [3] | Tunis (Tunisia) | 2.3 |
| [3] | Berber (Morocco) | 1.4 |
| [3] | Rimaibe (Burkina Faso) | 1.1 |
| [3] | New Delhi (India) | 0.8 |
| [3] | Lisu (Yunnan, China) | 0.7 |
| [3] | Beti (Cameroon) | 0.6 |
| [3] | Majorca & Minorca (Spain) | 0.6 |
| [3] | Gypsy (E. Andalusia, Spain) | 0.5 |
| [3] | Tunisia | 0.5 |
| [3] | Romanian | 0.3 |
| [3] | Northeast Thailand | 0.2 |
| [3] | Tibet (China) | 0.6 |
| ' | ||
| HLA B*7802 frequencies | ||
| [3] | Svans (Georgia) | 0.6 |
| [3] | Arab Druse (Israel) | 0.5 |
| [3] | Delhi (India) | 0.5 |
| [3] | Southern Han (China) | 0.2 |
| [3] | Beijing (China) | 0.1 |
References
[edit]- ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j k l m n o p q r s t u v w Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
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