Chondroitin
A chondroitin is a chondrin derivative.[1]
Types include:
Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis.[2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine.[2] Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules.[3] The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal.[3] Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.[4] However, the effectiveness of the drugs is still doubtful.[3]
References
[edit]- ^ Chondroitin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ a b Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis". World Journal of Orthopedics. 8 (1): 1–11. doi:10.5312/wjo.v8.i1.1. ISSN 2218-5836. PMC 5241539. PMID 28144573.
- ^ a b c Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy. 80 (10): 1049.
- ^ Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials". Journal of Orthopaedic Surgery and Research. 13 (1): 170. doi:10.1186/s13018-018-0871-5. ISSN 1749-799X. PMC 6035477. PMID 29980200.
| Unsulfated, extracellular | |
|---|---|
| Sulfated, extracellular | |
| Sulfated, intracellular | |
| Synthetic | |
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