COG8

COG8
Identifiers
Aliases	COG8, CDG2H, DOR1, component of oligomeric golgi complex 8
External IDs	OMIM: 606979; MGI: 2142885; HomoloGene: 13018; GeneCards: COG8; OMA:COG8 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	69,339,667 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	107,783,321 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; tibialis anterior muscle; ; stromal cell of endometrium; ; gastrocnemius muscle; ; mucosa of ileum; ; right adrenal gland; ; cerebellar vermis; ; right adrenal cortex; ; muscle of thigh; ; left adrenal gland;
	Top expressed in
	otic vesicle; ; saccule; ; seminiferous tubule; ; otic placode; ; spermatid; ; spermatocyte; ; muscle of thigh; ; granulocyte; ; interventricular septum; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	membrane; Golgi transport complex; trans-Golgi network membrane; Golgi membrane; Golgi apparatus;
Biological process	protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	84342
	97484
	ENSG00000213380
	ENSMUSG00000031916
	Q96MW5
	Q9JJA2
	NM_032382; NM_001374871
	NM_139229
	NP_115758
	NP_631975
	Wikidata
View/Edit Human	View/Edit Mouse

Conserved oligomeric Golgi complex subunit 8 is a protein that in humans is encoded by the COG8 gene.^[5]^[6]

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi complex (COG), which includes COG8 (Ungar et al., 2002).[supplied by OMIM]^[6]

References