CDD-2807
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| Chemical and physical data | |
| Formula | C29H26N4O |
| Molar mass | 446.554 g·mol−1 |
| 3D model (JSmol) | |
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CDD-2807 is a chemical compound which acts as a potent and selective inhibitor of serine/threonine-protein kinase 33 (STK33), with a IC50 of 9.2 nM. In animal studies it causes production of abnormal sperm with reduced motility, and it has been investigated as a potential male contraceptive drug.[1][2]
See also
[edit]References
[edit]- ^ Holdaway J, Georg GI (May 2024). "An emerging target for male contraception". Science. 384 (6698): 849–850. doi:10.1126/science.adp6432. PMID 38781397.
- ^ Ku AF, Sharma KL, Ta HM, Sutton CM, Bohren KM, Wang Y, et al. (May 2024). "Reversible male contraception by targeted inhibition of serine/threonine kinase 33". Science. 384 (6698): 885–890. doi:10.1126/science.adl2688. PMID 38781365.
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