For faster navigation, this Iframe is preloading the Wikiwand page for Aloe emodin.

Aloe emodin

Aloe emodin
Clinical data
Other namesRhabarberone
Routes of
administration
Oral
ATC code
  • None
Identifiers
  • 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.884 Edit this at Wikidata
Chemical and physical data
FormulaC15H10O5
Molar mass270.240 g·mol−1
3D model (JSmol)
Melting point223 to 224 °C (433 to 435 °F) Sublimes in CO2 stream
  • O=C2c1cccc(O)c1C(=O)c3c2cc(cc3O)CO
  • InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2 checkY
  • Key:YDQWDHRMZQUTBA-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.[1] Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kinds of radiation.[2][3]

Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of Frangula (Rhamnus frangula) and cascara sagrada (Rhamnus purshiana), the leaves of Senna (Cassia angustifolia), and the rhizome of rhubarb (Rheum rhaponticum).[citation needed] Aloe-emodin has not been found in Natal aloes.[citation needed]

References

  1. ^ The Merck Index (12th ed.). p. 313.
  2. ^ Badgwell DB, Walker CM, Baker WT, Strickland FM (March 2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular Carcinogenesis. 39 (3): 127–38. doi:10.1002/mc.10170. PMID 14991742. S2CID 24146785.
  3. ^ National Toxicology Program (September 2010). "Photocarcinogenesis study of aloe vera [CAS NO. 481-72-1(Aloe-emodin)] in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program Technical Report Series (553): 7–33, 35–97, 99-103 passim. PMID 21031007.

See also

{{bottomLinkPreText}} {{bottomLinkText}}
Aloe emodin
Listen to this article

This browser is not supported by Wikiwand :(
Wikiwand requires a browser with modern capabilities in order to provide you with the best reading experience.
Please download and use one of the following browsers:

This article was just edited, click to reload
This article has been deleted on Wikipedia (Why?)

Back to homepage

Please click Add in the dialog above
Please click Allow in the top-left corner,
then click Install Now in the dialog
Please click Open in the download dialog,
then click Install
Please click the "Downloads" icon in the Safari toolbar, open the first download in the list,
then click Install
{{::$root.activation.text}}

Install Wikiwand

Install on Chrome Install on Firefox
Don't forget to rate us

Tell your friends about Wikiwand!

Gmail Facebook Twitter Link

Enjoying Wikiwand?

Tell your friends and spread the love:
Share on Gmail Share on Facebook Share on Twitter Share on Buffer

Our magic isn't perfect

You can help our automatic cover photo selection by reporting an unsuitable photo.

This photo is visually disturbing This photo is not a good choice

Thank you for helping!


Your input will affect cover photo selection, along with input from other users.

X

Get ready for Wikiwand 2.0 🎉! the new version arrives on September 1st! Don't want to wait?