ADAM23
ADAM23 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ADAM23, MDC-3, MDC3, ADAM metallopeptidase domain 23 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603710; MGI: 1345162; HomoloGene: 2826; GeneCards: ADAM23; OMA:ADAM23 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Disintegrin and metalloproteinase domain-containing protein 23 is a non-catalytic protein that in humans is encoded by the ADAM23 gene.[5][6] It is a member of the ADAM family of extracellular matrix metalloproteinases.
Function
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.[6]
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