Singles
2021 Vesuvio Cup
Final
Champion	Tallon Griekspoor
Runner-up	Alexander Ritschard
Score	6–3, 6–2
Events
Singles Doubles
Vesuvio Cup · 2022 →

This was the first edition of the tournament.^[1]

Tallon Griekspoor won the title after defeating Alexander Ritschard 6–3, 6–2 in the final.

	Semifinals							Final
	5	Tallon Griekspoor	6	6
		Flavio Cobolli	4	4
								5	Tallon Griekspoor	6	6
								Q	Alexander Ritschard	3	2
		Franco Agamenone	3	3
	Q	Alexander Ritschard	6	6

	First round							Second round							Quarterfinals							Semifinals
	1	F Coria	6	6
	Alt	A Arnaboldi	4	2				1	F Coria	2	2
	WC	J Berrettini	5	77	4				M Guinard	6	6
		M Guinard	7	65	6											M Guinard	67	6	3
	Q	Á López San Martín	6	6											5	T Griekspoor	79	3	6
		T Skatov	3	2				Q	Á López San Martín	3	3
		B Rola	2	66				5	T Griekspoor	6	6
	5	T Griekspoor	6	78																		5	T Griekspoor	6	6
	LL	E Furness	1	1																			F Cobolli	4	4
	WC	M Arnaldi	6	6				WC	M Arnaldi	1	6	2
		D Ajduković	5	3					F Cobolli	6	3	6
		F Cobolli	7	6												F Cobolli	6	3	7
		L Giustino	6	6												L Giustino	4	6	5
		N Serdarušić	4	1					L Giustino	6	5	7
		M Bašić	3	6	5			6	A Martin	4	7	5
	6	A Martin	6	4	7

	First round							Second round							Quarterfinals							Semifinals
	7	B Zapata Miralles	6	6
		A Pellegrino	3	1				7	B Zapata Miralles	77	6
		A Müller	6	3	6				A Müller	60	0
	PR	F Baldi	1	6	2										7	B Zapata Miralles	3	0
		M Bourgue	6	6												F Agamenone	6	6
	Q	L Darderi	2	4					M Bourgue	7	63	1
		F Agamenone	6	2	6				F Agamenone	5	77	6
	3	H Gaston	4	6	3																		F Agamenone	3	3
	8	Y Hanfmann	6	5	6																	Q	A Ritschard	6	6
	WC	R Brancaccio	4	7	2			8	Y Hanfmann	3	6	4
	Q	A Ritschard	6	6				Q	A Ritschard	6	4	6
		J Clarke	0	1											Q	A Ritschard	0	77	6
	Q	J Forejtek	3	4												GM Moroni	6	61	3
		GM Moroni	6	6					GM Moroni	3	6	6
		M-A Hüsler	6	3	2			2	M Cecchinato	6	1	4
	2	M Cecchinato	4	6	6

• Main draw
• Qualifying draw