Singles
2021 Challenger La Manche
Final
Champion	Ruben Bemelmans
Runner-up	Lukáš Rosol
Score	6–4, 6–4
Events
Singles Doubles
← 2020 · Challenger La Manche · 2022 →

Roman Safiullin was the defending champion^[1] but chose not to defend his title.

Ruben Bemelmans won the title after defeating Lukáš Rosol 6–4, 6–4 in the final.

	Semifinals							Final
		Ruben Bemelmans	6	3	7
	3	Arthur Rinderknech	3	6	5
									Ruben Bemelmans	6	6
									Lukáš Rosol	4	4
		Hugo Gaston	5	6	3
		Lukáš Rosol	7	2	6

	First round							Second round							Quarterfinals							Semifinals
	1	D Kudla	6	6
	Alt	N Serdarušić	3	1				1	D Kudla	1	77	3
	Q	M Geerts	62	6	6			Q	M Geerts	6	65	6
	Q	J Forejtek	77	4	2										Q	M Geerts	6	1	64
		R Bemelmans	3	6	6											R Bemelmans	4	6	77
	LL	C Denolly	6	1	4				R Bemelmans	6	77
		D Istomin	6	5	6				D Istomin	4	64
	Q	N Lammons	3	7	4																		R Bemelmans	6	3	7
	3	A Rinderknech	4	6	6																	3	A Rinderknech	3	6	5
		A Vatutin	6	0	3			3	A Rinderknech	77	6
		I Sijsling	2	4				WC	E Furness	65	3
	WC	E Furness	6	6											3	A Rinderknech	77	77
		C Lestienne	1	6	6											C Lestienne	64	63
	Q	T Droguet	6	1	2				C Lestienne	6	6
	WC	M Martineau	714	6				WC	M Martineau	3	4
	6	B Zapata Miralles	612	3

	First round							Second round							Quarterfinals							Semifinals
	5	P Gojowczyk	6	6
		T-l Wu	2	4				5	P Gojowczyk	6	3	2
		J Lenz	1	6	3				H Gaston	4	6	6
		H Gaston	6	3	6											H Gaston	6	6
		G Oliveira	1	4											Alt	L Klein	0	3
	Alt	L Klein	6	6				Alt	L Klein	4	6	6
	WC	K de Schepper	5	6	3			4	J Rodionov	6	1	3
	4	J Rodionov	7	3	6																		H Gaston	5	6	3
	8	S Ofner	6	6																			L Rosol	7	2	6
		Y Maden	1	3				8	S Ofner	3	2
		M Janvier	64	0r					K Żuk	6	6
		K Żuk	77	1												K Żuk	62	6	62
		L Rosol	1	6	78											L Rosol	77	4	77
	Alt	A Molčan	6	3	66				L Rosol	6	5	7
		M Trungelliti	1	0				2	A Hoang	3	7	5
	2	A Hoang	6	6

• Main draw
• Qualifying draw